Patient Knowledge and Attitudes towards Genetic Testing in Parkinson’s Disease Subjects with Deep Brain Stimulation
المؤلفون المشاركون
Fraint, Avram
Ouyang, Bichun
Metman, Leonard Verhagen
Jones, Carolyn
Hall, Deborah A.
Marder, Karen
Pal, Gian
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-04-21
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Objectives.
As genetic testing is becoming more widely commercially available for Parkinson’s disease (PD) and may have implications regarding clinical outcomes for deep brain stimulation (DBS) and other therapies, we aimed to determine patient knowledge and attitudes towards genetic testing.
Methods.
A sample of 88 PD subjects with bilateral STN-DBS completed a Genetic Attitudes Questionnaire (GAQ).
Knowledge and attitudes towards genetic testing were assessed.
Results.
The mean percent of correct responses regarding genetic testing knowledge was 58.5%.
Nearly 90% of subjects were unfamiliar with Genetic Information Nondiscrimination Act (GINA).
The most important reasons subjects cited in deciding whether to undergo genetic testing included (1) to be a candidate for clinical trials if positive, (2) to learn that they do not carry a mutation, and (3) because a healthcare provider had recommended it.
Individuals who influence decision-making include spouses and children.
About 88% of subjects would share results with spouses, children, and siblings.
Discussion.
These results reveal that there is a major knowledge gap regarding genetic testing in PD and the implications of testing results on treatment, work, insurance, and privacy.
Also, subjects would mainly seek genetic testing to participate in clinical trials, with spouses and children being the key stakeholders in decision-making.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Fraint, Avram& Ouyang, Bichun& Metman, Leonard Verhagen& Jones, Carolyn& Hall, Deborah A.& Marder, Karen…[et al.]. 2019. Patient Knowledge and Attitudes towards Genetic Testing in Parkinson’s Disease Subjects with Deep Brain Stimulation. Parkinson’s Disease،Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1206896
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Fraint, Avram…[et al.]. Patient Knowledge and Attitudes towards Genetic Testing in Parkinson’s Disease Subjects with Deep Brain Stimulation. Parkinson’s Disease No. 2019 (2019), pp.1-6.
https://search.emarefa.net/detail/BIM-1206896
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Fraint, Avram& Ouyang, Bichun& Metman, Leonard Verhagen& Jones, Carolyn& Hall, Deborah A.& Marder, Karen…[et al.]. Patient Knowledge and Attitudes towards Genetic Testing in Parkinson’s Disease Subjects with Deep Brain Stimulation. Parkinson’s Disease. 2019. Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1206896
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1206896
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر