Enhanced Motivational Modulation of Motor Behaviour with Subthalamic Nucleus Deep Brain Stimulation in Parkinson’s Disease
المؤلفون المشاركون
Jahanshahi, Marjan
Kojovic, Maja
Higgins, Andrea
Mir, P.
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-01-02
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
Motivational improvement of movement speed in Parkinson’s disease (PD) is observed in life-threatening situations and has been empirically demonstrated in experimental studies using reaction time paradigms.
Objectives.
To address two clinically relevant questions: first, if in PD, motivational modulation through provision of monetary incentive on a sorting task that approximates performance on everyday life tasks affects movement speed.
Second, how this effect is compared between PD patients treated with medication or subthalamic deep brain stimulation.
Methods.
We used the Card Arranging Reward Responsivity Objective Test that shares component processes with everyday life tasks to compare reward responsivity of movement speed in 10 PD patients with STN-DBS, 10 nonoperated medicated PD patients, both OFF and ON their usual medications/stimulation, and 11 age-matched healthy controls.
Results.
Despite longer disease duration and more severe motor symptoms, STN-DBS PD patients with the stimulator turned ON showed greater improvement of movement speed with the prospect of monetary incentive compared to both medicated PD patients and healthy participants.
Discussion.
The effect of monetary incentive on movement speed in PD patients is more pronounced with STN-DBS than dopaminergic medications, suggesting that motivational modulation of movement speed may be enhanced as a direct consequence of STN stimulation.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kojovic, Maja& Higgins, Andrea& Mir, P.& Jahanshahi, Marjan. 2019. Enhanced Motivational Modulation of Motor Behaviour with Subthalamic Nucleus Deep Brain Stimulation in Parkinson’s Disease. Parkinson’s Disease،Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1206898
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kojovic, Maja…[et al.]. Enhanced Motivational Modulation of Motor Behaviour with Subthalamic Nucleus Deep Brain Stimulation in Parkinson’s Disease. Parkinson’s Disease No. 2019 (2019), pp.1-6.
https://search.emarefa.net/detail/BIM-1206898
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kojovic, Maja& Higgins, Andrea& Mir, P.& Jahanshahi, Marjan. Enhanced Motivational Modulation of Motor Behaviour with Subthalamic Nucleus Deep Brain Stimulation in Parkinson’s Disease. Parkinson’s Disease. 2019. Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1206898
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1206898
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر