Open-Label Placebo Trial among Japanese Patients with Chronic Low Back Pain
المؤلفون المشاركون
Deie, Masataka
Hayashi, Kazuhiro
Ikemoto, Tatsunori
Ueno, Takefumi
Arai, Young-Chang
Wakao, Norimitsu
Hirasawa, Atsuhiko
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-12-28
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Background.
The aim of this study was to confirm the effectiveness of open-label placebo (OLP) in Japanese patients with chronic low back pain (CLBP), similar to previous reports, and to investigate its short- and medium-term effects in this study population.
Methods.
Fifty-two patients with CLBP were randomized into a treatment as usual (TAU) group (n = 26) or an OLP + TAU group (n = 26) for 12 weeks.
The TAU included advice to remain active and exercise in conjunction with recent psychological education based on a self-management strategy.
In contrast, participants in the OLP + TAU group were instructed to take two OLP capsules a day.
Outcome measures were assessed at baseline and at weeks 3 and 12 using the Roland–Morris Disability Questionnaire (RMDQ), Numerical Rating Scale (NRS) for pain intensity, and the Timed-Up-and-Go (TUG) test.
Difference in outcomes between the two groups was compared at the two follow-up points.
Results.
Although all participants completed the 3-week follow-up, four patients (two in each group) were lost to follow-up beyond week 3.
There were no significant intergroup differences in changes in the RMDQ score (p=0.40), pain-NRS score (p=0.19), and TUG time (p=0.98) at week 3.
Two-way repeated measure analyses of covariance showed significant time-course effects but did not show group effects or any interactions between the time-course and group in terms of the RMDQ score.
However, it did not show any effects in the pain-NRS score and TUG time at week 12.
Conclusions.
The OLP + TAU group showed no superior findings in comparison with the TAU group after 3 weeks and 12 weeks for Japanese patients with CLBP.
Nonetheless, significant improvements in functional disability were observed in both groups.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ikemoto, Tatsunori& Ueno, Takefumi& Arai, Young-Chang& Wakao, Norimitsu& Hirasawa, Atsuhiko& Hayashi, Kazuhiro…[et al.]. 2020. Open-Label Placebo Trial among Japanese Patients with Chronic Low Back Pain. Pain Research and Management،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1206936
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ikemoto, Tatsunori…[et al.]. Open-Label Placebo Trial among Japanese Patients with Chronic Low Back Pain. Pain Research and Management No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1206936
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ikemoto, Tatsunori& Ueno, Takefumi& Arai, Young-Chang& Wakao, Norimitsu& Hirasawa, Atsuhiko& Hayashi, Kazuhiro…[et al.]. Open-Label Placebo Trial among Japanese Patients with Chronic Low Back Pain. Pain Research and Management. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1206936
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1206936
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر