Molecular Aspects of Regional Pain Syndrome
المؤلفون المشاركون
Bertelli, M.
Baronio, Manuela
Sadia, Hajra
Paolacci, Stefano
Prestamburgo, Domenico
Miotti, Danilo
Guardamagna, Vittorio A.
Natalini, Giuseppe
Sullivan, Stephanie G. B.
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-04-11
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
The purpose of this review is to summarize the pathophysiology of complex regional pain syndrome (CRPS), the underlying molecular mechanisms, and potential treatment options for its management.
CRPS is a multifactorial pain condition.
CRPS is characterized by prolonged or excessive pain and changes in skin color and temperature, and/or swelling in the affected area, and is generally caused by stimuli that lead to tissue damage.
An inflammatory response involving various cytokines and autoantibodies is generated in response to acute trauma/stress.
Chronic phase pathophysiology is more complex, involving the central and peripheral nervous systems.
Various genetic factors involved in the chronicity of pain have been identified in CRPS patients.
As with other diseases of complex pathology, CRPS is difficult to treat and no single treatment regimen is the same for two patients.
Stimulation of the vagus nerve is a promising technique being tested for different gastrointestinal and inflammatory diseases.
CRPS is more frequent in individuals of 61–70 years of age with a female to male ratio of 3 : 1.
Menopause, migraine, osteoporosis, and asthma all represent risk factors for CRPS and in smokers the prognosis appears to be more severe.
The pathophysiological mechanisms underlying CRPS involve both inflammatory and neurological pathways.
Understanding the molecular basis of CRPS is important for its diagnosis, management, and treatment.
For instance, vagal nerve stimulation might have the potential for treating CRPS through the cholinergic anti-inflammatory pathway.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Baronio, Manuela& Sadia, Hajra& Paolacci, Stefano& Prestamburgo, Domenico& Miotti, Danilo& Guardamagna, Vittorio A.…[et al.]. 2020. Molecular Aspects of Regional Pain Syndrome. Pain Research and Management،Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1206999
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Baronio, Manuela…[et al.]. Molecular Aspects of Regional Pain Syndrome. Pain Research and Management No. 2020 (2020), pp.1-10.
https://search.emarefa.net/detail/BIM-1206999
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Baronio, Manuela& Sadia, Hajra& Paolacci, Stefano& Prestamburgo, Domenico& Miotti, Danilo& Guardamagna, Vittorio A.…[et al.]. Molecular Aspects of Regional Pain Syndrome. Pain Research and Management. 2020. Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1206999
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1206999
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر