Combination of Alcohol and EVOH as a New Embolic Agent: Midterm Tissue and Inflammatory Effects in a Swine Model
المؤلفون المشاركون
Hak, Jean-François
Tradi, Farouk
Bobot, Mickael
Brige, Pauline
Habert, Paul
Chopinet, Sophie
Haffner, Aurélie
Guillet, Benjamin
Vidal, Vincent
Soulez, Gilles
المصدر
Radiology Research and Practice
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-10-26
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Objective.
To evaluate the vascular occlusion and midterm tissue toxicity properties of a combination of ethylene-vinyl alcohol (EVOH) (Squid 18®) (75%) and alcohol (25%)—Alco-Squid 18—in a swine model.
Materials and Methods.
Alco-Squid 18 (75% Squid 18® mixed with 25% alcohol) (AS18) was compared to embolization with 96% alcohol alone and to embolization with Squid 18® (S18®) alone.
An arteriovenous malformation (AVM) model was created in group 1 (n = 2).
Each AVM model was then embolized with AS18 or S18® alone with evaluation of a ratio between the volume of embolic agent divided by the volume of the AVM (evaluated by CT).
For group 2 (n = 5), each agent was tested on three different kidneys (upper pole kidney artery).
Pre- and postinterventional CTs, angiographies, blood alcohol content dosages, and histological studies (3 months postintervention) were performed.
Results.
AS18 has better distal distribution than S18® alone, both in the kidneys (mean capsule-S18® distance: 3.9 mm (±0.23) and mean capsule-AS18 distance: 2.3 mm (±0.11) (p=0.029) and in the AVM model.
Histological exploration found a higher rate of tubular necrosis with AS18 compared with S18® alone and alcohol alone (3.78 ± 0.44 compared to 2.33 ± 1.22 p = 0.012 and 1.22 ± 0.67 p <0 .0001).
The blood alcohol content was negligible in all cases.
Conclusion.
AS18 can suggest a better distal sclerotic and embolic character as compared with S18® alone without systemic toxicity.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hak, Jean-François& Tradi, Farouk& Bobot, Mickael& Brige, Pauline& Habert, Paul& Chopinet, Sophie…[et al.]. 2020. Combination of Alcohol and EVOH as a New Embolic Agent: Midterm Tissue and Inflammatory Effects in a Swine Model. Radiology Research and Practice،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1207235
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hak, Jean-François…[et al.]. Combination of Alcohol and EVOH as a New Embolic Agent: Midterm Tissue and Inflammatory Effects in a Swine Model. Radiology Research and Practice No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1207235
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hak, Jean-François& Tradi, Farouk& Bobot, Mickael& Brige, Pauline& Habert, Paul& Chopinet, Sophie…[et al.]. Combination of Alcohol and EVOH as a New Embolic Agent: Midterm Tissue and Inflammatory Effects in a Swine Model. Radiology Research and Practice. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1207235
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1207235
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر