Time Trends and Prognostic Factors for Overall Survival in Myxoid Liposarcomas: A Population-Based Study
المؤلفون المشاركون
Lansu, Jules
Van Houdt, Winan J.
Schaapveld, Michael
Walraven, Iris
Van de Sande, Michiel A. J.
Ho, Vincent K. Y.
Haas, Rick L.
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-09-22
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Background.
The purpose of this study was to evaluate the overall survival (OS) and associated characteristics for patients with Myxoid Liposarcoma (MLS) over time in The Netherlands.
Methods.
A population-based study was performed of patients with primary localized (n = 851) and metastatic (n = 50) MLS diagnosed in The Netherlands between 1989 and 2016, based on data from the National Cancer Registry.
Results.
The median age of the MLS patients was 49 years, and approximately two-thirds was located in the lower limb.
An association was revealed between age and the risk of having a Round Cell (RC) tumor.
OS rates for primary localized MLS were 93%, 83%, 78%, and 66% after 1, 3, 5, and 10 years, respectively.
The median OS for patients with metastatic disease at diagnosis was 10 months.
Increasing age (Hazard Ratio (HR) 1.05, p=0.00), a tumor size >5 cm (HR 2.18; p=0.00), and tumor location (trunk HR 1.29; p=0.09, upper limb HR 0.83; p=0.55, and “other” locations HR 2.73; p=0.00, as compared to lower limb) were independent prognostic factors for OS.
The percentage of patients treated with radiotherapy (RT) increased over time, and preoperative RT gradually replaced postoperative RT.
In contrast to patients with localized disease, significant improvement of OS was observed in patients with metastatic disease over time.
Conclusions.
In this large nationwide cohort, tumor size and tumor location were independent prognostic factors for OS.
Furthermore, a higher probability of an RC tumor with increasing age was suggested.
An increased use of RT over the years did not translate into improved OS for localized MLS.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Lansu, Jules& Van Houdt, Winan J.& Schaapveld, Michael& Walraven, Iris& Van de Sande, Michiel A. J.& Ho, Vincent K. Y.…[et al.]. 2020. Time Trends and Prognostic Factors for Overall Survival in Myxoid Liposarcomas: A Population-Based Study. Complexity،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1207279
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Lansu, Jules…[et al.]. Time Trends and Prognostic Factors for Overall Survival in Myxoid Liposarcomas: A Population-Based Study. Complexity No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1207279
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Lansu, Jules& Van Houdt, Winan J.& Schaapveld, Michael& Walraven, Iris& Van de Sande, Michiel A. J.& Ho, Vincent K. Y.…[et al.]. Time Trends and Prognostic Factors for Overall Survival in Myxoid Liposarcomas: A Population-Based Study. Complexity. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1207279
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1207279
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر