![](/images/graphics-bg.png)
Prognostic Factors for Development of Subsequent Metastases in Localized Osteosarcoma: A Systematic Review and Identification of Literature Gaps
المؤلفون المشاركون
Basile, Patrick
Greengard, Emily
Weigel, Brenda
Spector, Logan
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-03-27
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Aim.
To investigate prognostic factors in pediatric and young adult patients with localized osteosarcoma that could predict the development of subsequent pulmonary metastases and lead to an ability to risk-stratify therapy.
We performed a systematic review of the literature published since January 1990 to establish common evidence-based prognostic factors.
Methods.
PubMed and Embase searches (Jan 1990–Aug 2018) were performed.
Two reviewers independently selected papers for patients with localized osteosarcoma with subsequent metastatic development and then reviewed for quality of methods and prognostic factors.
Results.
Database searches yielded 216 unique results.
After screening, 27 full-text articles were studied in depth, with 9 items fulfilling predetermined inclusion and exclusion criteria.
Age, tumor location, tumor size/volume, and histologic response carried independent prognostic value in the majority of the studies.
Conclusions.
Several prognostic factors seemed to be consistent amongst the studies, but the heterogeneity and smaller sizes of the study populations made pooling of results difficult.
Standardization of larger patient populations and consistent definitions/cutoffs for prognostic factors are needed to further assess for consistent prognostic factors and potential predictive models to be developed.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Basile, Patrick& Greengard, Emily& Weigel, Brenda& Spector, Logan. 2020. Prognostic Factors for Development of Subsequent Metastases in Localized Osteosarcoma: A Systematic Review and Identification of Literature Gaps. Complexity،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1207351
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Basile, Patrick…[et al.]. Prognostic Factors for Development of Subsequent Metastases in Localized Osteosarcoma: A Systematic Review and Identification of Literature Gaps. Complexity No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1207351
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Basile, Patrick& Greengard, Emily& Weigel, Brenda& Spector, Logan. Prognostic Factors for Development of Subsequent Metastases in Localized Osteosarcoma: A Systematic Review and Identification of Literature Gaps. Complexity. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1207351
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1207351
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)