Differentiating Induced Pluripotent Stem Cells into Renal Cells: A New Approach to Treat Kidney Diseases
المؤلفون المشاركون
Caldas, Heloisa Cristina
de Carvalho Ribeiro, Patrícia
Oliveira, Lucas Felipe
Filho, Mario Abbud
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-08-07
دولة النشر
مصر
عدد الصفحات
9
الملخص EN
Renal disease is a major issue for global public health.
Despite some progress in supportive care, the mortality rates among patients with this condition remain alarmingly high.
Studies in pursuit of innovative strategies to treat renal diseases, especially stimulating kidney regeneration, have been developed.
In this field, stem cell-based therapy has been a promising area.
Induced pluripotent stem cell-derived renal cells (iPSC-RCs) represent an interesting source of cells for treating kidney diseases.
Advances in regenerative medicine using iPSC-RCs and their application to the kidney are discussed in this review.
Furthermore, the way differentiation protocols of induced pluripotent stem cells into renal cells may also be applied for the generation of kidney organoids is also described, contributing to studies in renal development, kidney diseases, and drug toxicity tests.
The translation of the differentiation methodologies into animal model studies and the safety and feasibility of renal differentiated cells as a treatment for kidney injury are also highlighted.
Although only few studies were published in this field, the results seem promising and support the use of iPSC-RCs as a potential therapy in the future.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
de Carvalho Ribeiro, Patrícia& Oliveira, Lucas Felipe& Filho, Mario Abbud& Caldas, Heloisa Cristina. 2020. Differentiating Induced Pluripotent Stem Cells into Renal Cells: A New Approach to Treat Kidney Diseases. Stem Cells International،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1208084
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
de Carvalho Ribeiro, Patrícia…[et al.]. Differentiating Induced Pluripotent Stem Cells into Renal Cells: A New Approach to Treat Kidney Diseases. Stem Cells International No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1208084
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
de Carvalho Ribeiro, Patrícia& Oliveira, Lucas Felipe& Filho, Mario Abbud& Caldas, Heloisa Cristina. Differentiating Induced Pluripotent Stem Cells into Renal Cells: A New Approach to Treat Kidney Diseases. Stem Cells International. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1208084
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1208084
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر