Structural and Functional Characterization of Deceased Donor Stem Cells: A Viable Alternative to Living Donor Stem Cells
المؤلفون المشاركون
Rao, Prakash N.
Deo, Dayanand D.
Marchioni, Misty A.
Cetrulo, Kyle
Sawczak, Sharyn
Myrick, Jacob
Taghizadeh, Rouzbeh R.
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-11-25
دولة النشر
مصر
عدد الصفحات
13
الملخص EN
Stem cells can be isolated from various human tissues including bone marrow (BM) and adipose tissue (AT).
Our study outlines a process to isolate adult stem cells from deceased donors.
We have shown that cell counts obtained from deceased donor BM were within established living donor parameters.
Evaluation of demographic information exhibited a higher percentage of hematopoietic stem cells (HSC) in males versus females, as well as a higher percentage of HSC in the age bracket of 25 years and under.
For the first time, we show that deceased donor femur BM grew cell colonies.
Our introduction of new technology for nonenzymatic AT processing significantly increased cell recovery over the traditional enzymatic processing method.
Cell counts from the deceased donor AT exceeded living donor parameters.
Furthermore, our data illustrated that AT from female donors yielded a much higher number of total nucleated cells (TNC) than males.
Together, our data demonstrates that our approach to isolate stem cells from deceased donors could be a routine practice to provide a viable alternative to living donor stem cells.
This will offer increased accessibility for patients awaiting stem cell therapies.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Rao, Prakash N.& Deo, Dayanand D.& Marchioni, Misty A.& Taghizadeh, Rouzbeh R.& Cetrulo, Kyle& Sawczak, Sharyn…[et al.]. 2019. Structural and Functional Characterization of Deceased Donor Stem Cells: A Viable Alternative to Living Donor Stem Cells. Stem Cells International،Vol. 2019, no. 2019, pp.1-13.
https://search.emarefa.net/detail/BIM-1209185
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Rao, Prakash N.…[et al.]. Structural and Functional Characterization of Deceased Donor Stem Cells: A Viable Alternative to Living Donor Stem Cells. Stem Cells International No. 2019 (2019), pp.1-13.
https://search.emarefa.net/detail/BIM-1209185
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Rao, Prakash N.& Deo, Dayanand D.& Marchioni, Misty A.& Taghizadeh, Rouzbeh R.& Cetrulo, Kyle& Sawczak, Sharyn…[et al.]. Structural and Functional Characterization of Deceased Donor Stem Cells: A Viable Alternative to Living Donor Stem Cells. Stem Cells International. 2019. Vol. 2019, no. 2019, pp.1-13.
https://search.emarefa.net/detail/BIM-1209185
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1209185
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر