![](/images/graphics-bg.png)
Functional Connectivity Alterations in Children with Spastic and Dyskinetic Cerebral Palsy
المؤلفون المشاركون
Yao, Dezhong
Luo, Cheng
He, Hui
Li, Jianfu
Qin, Yun
Sun, Bo
Zhang, Tao
Sun, Chengyan
Li, Yanan
Peng, Rui
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-14، 14ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-08-15
دولة النشر
مصر
عدد الصفحات
14
التخصصات الرئيسية
الملخص EN
Cerebral palsy (CP) has long been investigated to be associated with a range of motor and cognitive dysfunction.
As the two most common CP subtypes, spastic cerebral palsy (SCP) and dyskinetic cerebral palsy (DCP) may share common and distinct elements in their pathophysiology.
However, the common and distinct dysfunctional characteristics between SCP and DCP on the brain network level are less known.
This study aims to detect the alteration of brain functional connectivity in children with SCP and DCP based on resting-state functional MRI (fMRI).
Resting-state networks (RSNs) were established based on the independent component analysis (ICA), and the functional network connectivity (FNC) was performed on the fMRI data from 16 DCP, 18 bilateral SCP, and 18 healthy children.
Compared with healthy controls, altered functional connectivity within the cerebellum network, sensorimotor network (SMN), left frontoparietal network (LFPN), and salience network (SN) were found in DCP and SCP groups.
Furthermore, the disconnections of the FNC consistently focused on the visual pathway; covariance of the default mode network (DMN) with other networks was observed both in DCP and SCP groups, while the DCP group had a distinct connectivity abnormality in motor pathway and self-referential processing-related connections.
Correlations between the functional disconnection and the motor-related clinical measurement in children with CP were also found.
These findings indicate functional connectivity impairment and altered integration widely exist in children with CP, suggesting that the abnormal functional connectivity is a pathophysiological mechanism of motor and cognitive dysfunction of CP.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Qin, Yun& Li, Yanan& Sun, Bo& He, Hui& Peng, Rui& Zhang, Tao…[et al.]. 2018. Functional Connectivity Alterations in Children with Spastic and Dyskinetic Cerebral Palsy. Neural Plasticity،Vol. 2018, no. 2018, pp.1-14.
https://search.emarefa.net/detail/BIM-1210307
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Qin, Yun…[et al.]. Functional Connectivity Alterations in Children with Spastic and Dyskinetic Cerebral Palsy. Neural Plasticity No. 2018 (2018), pp.1-14.
https://search.emarefa.net/detail/BIM-1210307
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Qin, Yun& Li, Yanan& Sun, Bo& He, Hui& Peng, Rui& Zhang, Tao…[et al.]. Functional Connectivity Alterations in Children with Spastic and Dyskinetic Cerebral Palsy. Neural Plasticity. 2018. Vol. 2018, no. 2018, pp.1-14.
https://search.emarefa.net/detail/BIM-1210307
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1210307
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)