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Potential Roles of Dental Pulp Stem Cells in Neural Regeneration and Repair
المؤلفون المشاركون
Luo, Lihua
He, Yan
Wang, Xiaoyan
Key, Brian
Lee, Bae Hoon
Li, Huaqiong
Ye, Qingsong
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-15، 15ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-05-07
دولة النشر
مصر
عدد الصفحات
15
الملخص EN
This review summarizes current advances in dental pulp stem cells (DPSCs) and their potential applications in the nervous diseases.
Injured adult mammalian nervous system has a limited regenerative capacity due to an insufficient pool of precursor cells in both central and peripheral nervous systems.
Nerve growth is also constrained by inhibitory factors (associated with central myelin) and barrier tissues (glial scarring).
Stem cells, possessing the capacity of self-renewal and multicellular differentiation, promise new therapeutic strategies for overcoming these impediments to neural regeneration.
Dental pulp stem cells (DPSCs) derive from a cranial neural crest lineage, retain a remarkable potential for neuronal differentiation, and additionally express multiple factors that are suitable for neuronal and axonal regeneration.
DPSCs can also express immunomodulatory factors that stimulate formation of blood vessels and enhance regeneration and repair of injured nerve.
These unique properties together with their ready accessibility make DPSCs an attractive cell source for tissue engineering in injured and diseased nervous systems.
In this review, we interrogate the neuronal differentiation potential as well as the neuroprotective, neurotrophic, angiogenic, and immunomodulatory properties of DPSCs and its application in the injured nervous system.
Taken together, DPSCs are an ideal stem cell resource for therapeutic approaches to neural repair and regeneration in nerve diseases.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Luo, Lihua& He, Yan& Wang, Xiaoyan& Key, Brian& Lee, Bae Hoon& Li, Huaqiong…[et al.]. 2018. Potential Roles of Dental Pulp Stem Cells in Neural Regeneration and Repair. Stem Cells International،Vol. 2018, no. 2018, pp.1-15.
https://search.emarefa.net/detail/BIM-1213182
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Luo, Lihua…[et al.]. Potential Roles of Dental Pulp Stem Cells in Neural Regeneration and Repair. Stem Cells International No. 2018 (2018), pp.1-15.
https://search.emarefa.net/detail/BIM-1213182
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Luo, Lihua& He, Yan& Wang, Xiaoyan& Key, Brian& Lee, Bae Hoon& Li, Huaqiong…[et al.]. Potential Roles of Dental Pulp Stem Cells in Neural Regeneration and Repair. Stem Cells International. 2018. Vol. 2018, no. 2018, pp.1-15.
https://search.emarefa.net/detail/BIM-1213182
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1213182
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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