![](/images/graphics-bg.png)
In Vitro and In Vivo Comparison of Changes in Antibiotics Susceptibility of E. coli and Chicken’s Intestinal Flora after Exposure to Amoxicillin or Thymol
المؤلفون المشاركون
Hriouech, Soukayna
Mzabi, Aouatef
Chefchaou, Hanane
Tanghort, Mariam
Chami, Najat
Akhmouch, Ahmed A.
Remmal, Adnane
المصدر
Veterinary Medicine International
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-07-07
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
This study aims at verifying, in vitro, the extent to which the use of amoxicillin or thymol induces the selection of resistant bacteria and at evaluating in vivo their effects on the development of antimicrobial resistance in the intestinal flora of poultry.
E.
coli strain was subcultured on agar plates containing increasing concentrations of either amoxicillin or thymol.
Thereafter, minimal inhibitory concentrations (MICs) of thymol, amoxicillin, and two other antibiotics, tylosin and colistin, were determined using the microdilution method.
Groups of chicks were subjected to a 2-week regime of either amoxicillin or thymol added to their drinking water.
During the treatment with either thymol or amoxicillin, the total aerobic mesophilic flora (TAMF) was counted on thymol-gradient plates or amoxicillin-gradient plates and the MICs of antibiotics and thymol for E.
coli isolates were determined.
The in vitro test showed that for E.
coli, which had been serially subcultured on increasing concentrations of amoxicillin, a 32-fold increase in MIC values for amoxicillin and a 4-fold increase for colistin and tylosin were noted.
However, the MIC of thymol for this strain remained constant.
For the E.
coli, which had been serially subcultured on increasing concentrations of thymol, no change in the MIC values for antibiotics and thymol was observed.
The in vivo test confirmed the in vitro one.
It demonstrated that exposure to amoxicillin induced a selection of antimicrobial resistance in TAMF and intestinal E.
coli, whereas exposure to thymol did not.
The results showed that the group receiving thymol had a lower consumption index compared to the other groups.
This study demonstrates the feasibility of this natural product as an alternative solution to the current use of antibiotics in poultry farming.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hriouech, Soukayna& Akhmouch, Ahmed A.& Tanghort, Mariam& Chefchaou, Hanane& Mzabi, Aouatef& Chami, Najat…[et al.]. 2020. In Vitro and In Vivo Comparison of Changes in Antibiotics Susceptibility of E. coli and Chicken’s Intestinal Flora after Exposure to Amoxicillin or Thymol. Veterinary Medicine International،Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1214246
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hriouech, Soukayna…[et al.]. In Vitro and In Vivo Comparison of Changes in Antibiotics Susceptibility of E. coli and Chicken’s Intestinal Flora after Exposure to Amoxicillin or Thymol. Veterinary Medicine International No. 2020 (2020), pp.1-10.
https://search.emarefa.net/detail/BIM-1214246
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hriouech, Soukayna& Akhmouch, Ahmed A.& Tanghort, Mariam& Chefchaou, Hanane& Mzabi, Aouatef& Chami, Najat…[et al.]. In Vitro and In Vivo Comparison of Changes in Antibiotics Susceptibility of E. coli and Chicken’s Intestinal Flora after Exposure to Amoxicillin or Thymol. Veterinary Medicine International. 2020. Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1214246
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1214246
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)