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Preoperative Neutrophil-Lymphocyte Ratio and Platelet-Lymphocyte Ratio Are Not Clinically Useful in Predicting Prognosis in Early Stage Cervical Cancer
المؤلفون المشاركون
Hanprasertpong, Jitti
Nuchpramool, Prachratana
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-12-02
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Background.
An objective of this study was to determine the prognostic role of neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) in patients with cervical cancer (CC) stages IA2-IB1.
Methods.
The study included 484 patients who underwent radical hysterectomy with pelvic node dissection.
The associations of preoperative NLR and PLR with clinicopathologic characteristics and oncological outcomes were analyzed.
The cut-off values of NLR (=1.8) and PLR (=119) were set as medians.
Results.
The clinicopathologic analysis showed that NLR was associated with age (p=0.010), tumor size (p=0.045), and adjuvant treatment (p=0.005), and PLR was associated with only adjuvant treatment (p=0.033).
DFS and OS were not significantly different between patients with high and low NLR (p=0.670 and p=0.934) or high and low PLR (p=0.780 and p=0.306).
The independent prognostic factors associated with OS were lymph node status and anemia, and with DFS were histology, deep stromal invasion, and lymph node status.
Conclusions.
NLR and PLR have no use as prognostic biomarker for DFS and OS in early-stage CC.
However, NLR and PLR might be of use in determining the risk for adjuvant treatment.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Nuchpramool, Prachratana& Hanprasertpong, Jitti. 2018. Preoperative Neutrophil-Lymphocyte Ratio and Platelet-Lymphocyte Ratio Are Not Clinically Useful in Predicting Prognosis in Early Stage Cervical Cancer. Surgery Research and Practice،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1214824
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Nuchpramool, Prachratana& Hanprasertpong, Jitti. Preoperative Neutrophil-Lymphocyte Ratio and Platelet-Lymphocyte Ratio Are Not Clinically Useful in Predicting Prognosis in Early Stage Cervical Cancer. Surgery Research and Practice No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1214824
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Nuchpramool, Prachratana& Hanprasertpong, Jitti. Preoperative Neutrophil-Lymphocyte Ratio and Platelet-Lymphocyte Ratio Are Not Clinically Useful in Predicting Prognosis in Early Stage Cervical Cancer. Surgery Research and Practice. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1214824
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1214824
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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