Is Chemoprophylaxis for Child Contacts of Drug-Resistant TB Patients Beneficial? A Systematic Review
المؤلفون المشاركون
Burugina Nagaraja, Sharath
Chadha, Sarabjit
Das, Mrinalini
Rajendran, Mahalakshmi
Kirubakaran, Richard
Tharyan, Prathap
Padmapriyadarsini, C.
المصدر
Tuberculosis Research and Treatment
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-04-02
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Background.
Preventive therapy for child contacts of multidrug-resistant tuberculosis (MDR-TB) patients is poorly studied, and no consensus about the role and the rationale of chemoprophylaxis has been reached.
Objective.
To conduct systematic review with an aim to determine the effectiveness of TB preventive therapy in reducing the incidence of TB disease in pediatric contacts of MDR-TB patients.
Methods.
We conducted a literature search for randomized control trials, cohort studies, and case reports of chemoprophylaxis for pediatric contacts of MDR-TB patients in PubMed, EMBASE, Cochrane Databases of Systematic Reviews, metaRegister of Controlled Trials, and other clinical registries through March 2017, using appropriate search strategy.
In addition we searched abstracts from international conferences and references of published articles and reviews.
Results.
Of the 153 references assessed from various databases, seven studies were identified as relevant after adaption of eligibility criteria and assessed for systematic review.
Of these, only two studies contributed data for the pooled meta-analysis.
Conclusions.
Though the available evidences suggest that the chemoprophylaxis for child contacts of MDR-TB patients is beneficial, data to support or reject preventive therapy is very limited.
Further clinical research, in Tb endemic settings like India, needs to be performed to prove the beneficial effect of chemoprophylaxis for pediatric contacts of MDR-TB.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Padmapriyadarsini, C.& Das, Mrinalini& Burugina Nagaraja, Sharath& Rajendran, Mahalakshmi& Kirubakaran, Richard& Chadha, Sarabjit…[et al.]. 2018. Is Chemoprophylaxis for Child Contacts of Drug-Resistant TB Patients Beneficial? A Systematic Review. Tuberculosis Research and Treatment،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1215591
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Padmapriyadarsini, C.…[et al.]. Is Chemoprophylaxis for Child Contacts of Drug-Resistant TB Patients Beneficial? A Systematic Review. Tuberculosis Research and Treatment No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1215591
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Padmapriyadarsini, C.& Das, Mrinalini& Burugina Nagaraja, Sharath& Rajendran, Mahalakshmi& Kirubakaran, Richard& Chadha, Sarabjit…[et al.]. Is Chemoprophylaxis for Child Contacts of Drug-Resistant TB Patients Beneficial? A Systematic Review. Tuberculosis Research and Treatment. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1215591
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1215591
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر