Smear Microscopy for Diagnosis of Pulmonary Tuberculosis in Eastern Sudan
المؤلفون المشاركون
Shuaib, Yassir Adam
Schaible, Ulrich E.
Wieler, Lothar H.
Bakheit, Mohammed A. M.
Mohamed-Noor, Saad E.
Abdalla, Mohamed A.
Homolka, Susanne
Andres, Sönke
Hillemann, Doris
Lonnroth, Knut
Richter, Elvira
Niemann, Stefan
Kranzer, Katharina
Khidir, Selma Abdelmoneim
المصدر
Tuberculosis Research and Treatment
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-06-14
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Background.
In Sudan, tuberculosis diagnosis largely relies on clinical symptoms and smear microscopy as in many other low- and middle-income countries.
The aim of this study was to investigate the positive predictive value of a positive sputum smear in patients investigated for pulmonary tuberculosis in Eastern Sudan.
Methods.
Two sputum samples from patients presenting with symptoms suggestive of tuberculosis were investigated using direct Ziehl-Neelsen (ZN) staining and light microscopy between June to October 2014 and January to July 2016.
If one of the samples was smear positive, both samples were pooled, stored at −20°C, and sent to the National Reference Laboratory (NRL), Germany.
Following decontamination, samples underwent repeat microscopy and culture.
Culture negative/contaminated samples were investigated using polymerase chain reaction (PCR).
Results.
A total of 383 samples were investigated.
Repeat microscopy categorized 123 (32.1%) as negative, among which 31 were culture positive.
This increased to 80 when PCR and culture results were considered together.
A total of 196 samples were culture positive, of which 171 (87.3%), 14 (7.1%), and 11 (5.6%) were M.
tuberculosis, M.
intracellulare, and mixed species.
Overall, 15.6% (57/365) of the samples had no evidence of M.
tuberculosis, resulting in a positive predictive value of 84.4%.
Conclusions.
There was a discordance between the results of smear microscopy performed at local laboratories in the Sudan and at the NRL, Germany; besides, a considerable number of samples had no evidence of M.
tuberculosis.
Improved quality control for smear microscopy and more specific diagnostics are crucial to avoid possible overtreatment.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Shuaib, Yassir Adam& Khidir, Selma Abdelmoneim& Schaible, Ulrich E.& Wieler, Lothar H.& Bakheit, Mohammed A. M.& Mohamed-Noor, Saad E.…[et al.]. 2018. Smear Microscopy for Diagnosis of Pulmonary Tuberculosis in Eastern Sudan. Tuberculosis Research and Treatment،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1215597
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Shuaib, Yassir Adam…[et al.]. Smear Microscopy for Diagnosis of Pulmonary Tuberculosis in Eastern Sudan. Tuberculosis Research and Treatment No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1215597
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Shuaib, Yassir Adam& Khidir, Selma Abdelmoneim& Schaible, Ulrich E.& Wieler, Lothar H.& Bakheit, Mohammed A. M.& Mohamed-Noor, Saad E.…[et al.]. Smear Microscopy for Diagnosis of Pulmonary Tuberculosis in Eastern Sudan. Tuberculosis Research and Treatment. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1215597
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1215597
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر