Effect of garlic oil as a rodenticide for black rats Rattus rattus (Rodentia : Muridae)‎

الملخص EN

This research focuses on the toxicity study of the garlic oil in Rattus rattus (L.) (Rodentia: Muridae).

The used of 22 rats has been selected to study acute and chronic toxicity to start a trial in non- choice test.

Nine animals were used for 2, 4 and 8 % garlic oil bait for a preliminary experiment, and the 13 number, for 0.5,1 and 1.5% for the main experiment in nonchoice laboratory test.

Results indicated for a preliminary experiment that 2% of garlic oil highest toxicity concentrations after 48 hrs.

was recorded 40% and acceptability 44.45% .

It is very clear that the deadly effect of all concentrations according to the histopathology study on kidney and uterus was effective.

The main experiment, the high mortality percent of the rat was 60% for 1% garlic oil bait and acceptability 51.57 was recorded while in 1.5% garlic oil bait record 40% mortality and 46.16 acceptability.

Histopathological changes in kidney showing glomerular capillaries with very thin basement membrane mesangiolysis and destructed walls, uterus showed degeneration and necrosis of uterine gland and fibrosis in lamina propria of endometrium, the ovaries showed atrophy of the growing follicles and free from any stages of maturation.

The testis tubuli lumen exhibited necrosis and degeneration of sprmatogonium cells and epididymis free of spermatozoa and some of lumen full of degenerated necrosed.