Effects and association of Pro-oxidants with magnesium in patients with diabetic nephropathy
المؤلفون المشاركون
Kachhawa, Kamal
Kachhawa, Poonam
Agrawal, Divya
Sarkar, Purnima Dey
Kumar, Sanjay
المصدر
Saudi Journal of Kidney Diseases and Transplantation
العدد
المجلد 30، العدد 5 (31 أكتوبر/تشرين الأول 2019)، ص ص. 1032-1037، 6ص.
الناشر
تاريخ النشر
2019-10-31
دولة النشر
السعودية
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Diabetic nephropathy (DN) is the most common microvascular complication observed in patients with type-2 diabetes mellitus.
Furthermore, magnesium (Mg) deficiency is a common problem in diabetic patients.
In this study, we estimated the levels of Mg, which is an important trace element and pro-oxidant marker, and then evaluated the association between serum Mg and pro-oxidants in patients with DN.
In the present study, 200 patients were enrolled and were divided into two groups.
The control and DN groups consisted of 100 healthy individuals and 100 patients with DN, respectively.
Serum Mg, total anti-oxidant capacity (TAC), and superoxide dismutase (SOD) levels were estimated using the Calmagite, Koracevic, and Marklund and Marklund methods, respectively.
Glutathione (GSH) and malondialdehyde (MDA) levels were estimated using the Tietze F and Jean CD method, respectively.
Mg levels were found to be significantly decreased in the DN group in comparison to the control group.
Anti-oxidant markers were statistically significantly reduced (P <0.001), whereas MDA levels were statistically significantly elevated (P <0.001) in the DN group compared to the control group.
There was a significant positive association of Mg with TAC, SOD, and GSH.
A statistically significant negative association of Mg with MDA (r = −0.302, P <0.001, n = 100) was also observed.
An apparent relationship was observed between hypomagnesemia and oxidative stress in patients with DN.
Lower levels of Mg and oxidative stress were also strongly linked
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kachhawa, Kamal& Kachhawa, Poonam& Agrawal, Divya& Kumar, Sanjay& Sarkar, Purnima Dey. 2019. Effects and association of Pro-oxidants with magnesium in patients with diabetic nephropathy. Saudi Journal of Kidney Diseases and Transplantation،Vol. 30, no. 5, pp.1032-1037.
https://search.emarefa.net/detail/BIM-1256175
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kumar, Sanjay…[et al.]. Effects and association of Pro-oxidants with magnesium in patients with diabetic nephropathy. Saudi Journal of Kidney Diseases and Transplantation Vol. 30, no. 5 (Sep. / Oct. 2019), pp.1032-1037.
https://search.emarefa.net/detail/BIM-1256175
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kachhawa, Kamal& Kachhawa, Poonam& Agrawal, Divya& Kumar, Sanjay& Sarkar, Purnima Dey. Effects and association of Pro-oxidants with magnesium in patients with diabetic nephropathy. Saudi Journal of Kidney Diseases and Transplantation. 2019. Vol. 30, no. 5, pp.1032-1037.
https://search.emarefa.net/detail/BIM-1256175
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 1036-1037
رقم السجل
BIM-1256175
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر