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Sex and gender based differences in the incidence and surgical management of cancer : a literature review
العناوين الأخرى
الاختلافات في نسبة الحدوث و المعالجة الجراحية للسرطان على أساس الجنس و النوع الاجتماعي : مراجعة في المنشورات الطبية
المؤلفون المشاركون
al-Hamdani, Kazim Julub Hasan
Abd al-Aimmah, Ali Kamal
al-Amin, Mansur
المصدر
Journal of the Arab Board of Health Specializations
العدد
المجلد 21، العدد 2 (30 يونيو/حزيران 2020)، ص ص. 17-24، 8ص.
الناشر
المجلس العربي للاختصاصات الصحية
تاريخ النشر
2020-06-30
دولة النشر
سوريا
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Objectives: To study the impact of gender and sex on the incidence and management of malignant diseases.the period from 1985 to 2019 inclusive.
We studied the disparity related to sex and gender in the incidence, clinical presentation, response to surgical and chemotherapeutic treatment and the outcome in term of survival or mortality of malignant diseases.
This search yielded 325 articles, after independent manual review, 197potential articles were identified and fully reviewed, only 38 articles were included in this study, 128 articles were excluded.
Results: Gender and sex disparity in the incidence, presentation, aggressiveness, survival, mortality have been clearly noticed for a variety of cancers in both adults and children.
The incidence of fatal cases of malignancy, M:F ratio was 4:1 in respiratory tract, while it was 2:1 in oral cavity, tongue and urinary bladder.
In females; malignancy of breast, peritoneum, omentum, mesentery, thyroid, gallbladder, anus, anal canal, and anorectum had a higher incidence than in males.
Presentation disparity as in melanomas was more commonly noticed on the lower extremities in women while it was more often on the trunk and head and neck in men.
Male to female (M:F) cancer mortality rate in general was 1.46:1.0.
Sex differences in the response to chemotherapy and their side effects were noticed with an improved response in women.
Geographic distribution affects significantly male and female mortality in certain cancers such as pancreatic.
In childhood malignancy the prognosis was worse in boys than girls and the distribution of malignancy varies according to age subgroups.
Conclusions: Males; adults and children are more prone to develop cancer and have worse overall survival and higher mortality rates than females.
The significant survival advantage of women in several different cancer types was due to anatomical, hormonal and genetic differences.
Consideration of gender and sex is necessary and should be included in the clinical management of malignant cases to highlight understanding of biological differences between males and females and to avoid mistakes in diagnosis and management.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Hamdani, Kazim Julub Hasan& Abd al-Aimmah, Ali Kamal& al-Amin, Mansur. 2020. Sex and gender based differences in the incidence and surgical management of cancer : a literature review. Journal of the Arab Board of Health Specializations،Vol. 21, no. 2, pp.17-24.
https://search.emarefa.net/detail/BIM-1272032
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Hamdani, Kazim Julub Hasan…[et al.]. Sex and gender based differences in the incidence and surgical management of cancer : a literature review. Journal of the Arab Board of Health Specializations Vol. 21, no. 2 (2020), pp.17-24.
https://search.emarefa.net/detail/BIM-1272032
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Hamdani, Kazim Julub Hasan& Abd al-Aimmah, Ali Kamal& al-Amin, Mansur. Sex and gender based differences in the incidence and surgical management of cancer : a literature review. Journal of the Arab Board of Health Specializations. 2020. Vol. 21, no. 2, pp.17-24.
https://search.emarefa.net/detail/BIM-1272032
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Text in English ; abstracts in English and Arabic.
رقم السجل
BIM-1272032
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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