The efficacy of antivascular endothelial growth factor (Bivacizumab) pretreatment before vitrectomy for patients with complicated proliferative diabetic retinopathy
العناوين الأخرى
فعالية حقن عامل مضاد النمو الوعائي (بيفاسيزوماب) داخل الزجاجية قبل قطع زجاجية العين لتدبير اعتلال الشبكية السكري المنمي المختلط
المؤلف
المصدر
Damascus University Journal for Medical Sciences
العدد
المجلد 37، العدد 2 (30 يونيو/حزيران 2021)، ص ص. 1-6، 6ص.
الناشر
تاريخ النشر
2021-06-30
دولة النشر
سوريا
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background/aims: To evaluate the efficacy of antivascular endothelial growth factor (anti-VEGF) agents pretreatment before vitrectomy for patients with complicated proliferative diabetic retinopathy (PDR) Methods: A retrospective research was done on (29) Proliferative Diabetic Retinopathy (PDR) eyes who were divided into two groups, group A (n=19) Pars Plana Vitrectomy (PPV) with preoperative Intra Vitreous Bevacizumab (IVB ) and PPV group B (n=10).
Bevacizumab was injected 4-8 days before PPV.
Main outcome measures were visual acuity, incidence of iatrogenic retinal breaks, intraoperative bleeding ,surgery time and final tamponed.
Results: At six month after surgery, visual acuity in group A: IVB PPV (84.2%) and group B: PPV (80%) improved significantly and the difference between the two groups was not significant.
Iatrogenic retinal breaks were reported in 3 cases (15.7%) in group A and 4 cases (40%) in IVB group.
Intraoperative bleeding was encountered in all cases in two groups but it was less annoying in group A.
median surgery time was in group A 91 minute, and in group B 120 minute.
In group A13 eye ( 68.4%) was tamponed with Silicon oil while 6 eyes(31.5%) tamponed with air, and in group B all 10 eyes (100%) was tamponed with silicon oil.
Conclusion: The pretreatment of anti-VEGF agents before vitrectomy for patients with complicated PDR facilitates much faster surgery and better visual rehabilitation, reduces iatrogenic retinal breaks, and silicon oil tamponad.
Moreover, studies with larger sample sizes are required to further evaluation the efficacy of anti-VEGF agents and reach a firmer conclusion
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Awdah, Muhammad. 2021. The efficacy of antivascular endothelial growth factor (Bivacizumab) pretreatment before vitrectomy for patients with complicated proliferative diabetic retinopathy. Damascus University Journal for Medical Sciences،Vol. 37, no. 2, pp.1-6.
https://search.emarefa.net/detail/BIM-1273850
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Awdah, Muhammad. The efficacy of antivascular endothelial growth factor (Bivacizumab) pretreatment before vitrectomy for patients with complicated proliferative diabetic retinopathy. Damascus University Journal for Medical Sciences Vol. 37, no. 2 (2021), pp.1-6.
https://search.emarefa.net/detail/BIM-1273850
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Awdah, Muhammad. The efficacy of antivascular endothelial growth factor (Bivacizumab) pretreatment before vitrectomy for patients with complicated proliferative diabetic retinopathy. Damascus University Journal for Medical Sciences. 2021. Vol. 37, no. 2, pp.1-6.
https://search.emarefa.net/detail/BIM-1273850
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 6
رقم السجل
BIM-1273850
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر