Study the effect of garden cress and rosemary on experimental animals infected hyperglycemic

الملخص EN

This study was conducted to acquaintance the effectiveness of garden cress seeds and rosemary on experimental rats suffered from diabetes mellitus.48 adult male albino rats weighting between 150± 5 gram, rats were housed in cages arrows maintained at 25±2c and kept under normal healthy condition.

All rats will be fed on a standard diet for a week to acclimatization, and then dividedin to 8groups, each with 6 rats as follows: Group (1): (Nigative control )group 6 normal rats fed on basal diet, and the second group (2)(n=42): positive control infected rats alloxan (dose 150mg per kg).

Then rats were divided in to seven groups (each group consisted of 6 rats and fed on basal diet)as following: Group (2)was left as positive control(+)group.

Group (3): was fedon basal diet+3% of garden cress, Group (4): was fed on basal diet +6% of garden cress, Group (5)was fed on basal diet+3% of rosemary, Group (6): was fed on basal diet+6% of rosemary, Group (7): was fed on basal diet+3% mixture of garden cress and rosemary, Group (8): was fed on basal diet+6% mixture of garden cress and rosemary.

All above mentioned experimental groups were maintained on their corresponding diet for two months at the end of experimental rats were sacrificed and blood samples collected then centrifuged for Biochemicalanalysis: blood glucose, kidney function indicators, some serum liver enzymes activity and lipid profile were estimated.

(BWG), Feed efficiency ratio (FER)and relative orange weight were recorded.

Histopathological change for liver and kidney were estimated.

Also the proximate chemical composition for materials.

Conclusion: garden cress seeds and rosemary have therapeutic effect on diabetic rats.