The role of Toxoplasma gondii in concentration of some sex hormones in infertile individual
العناوين الأخرى
أثر الإصابة بطفيلي المقوسة القندية على تراكيز بعض الهرمونات الجنسية عند الأشخاص العقيمين
المؤلف
المصدر
Journal of Medical and Pharmaceutical Sciences
العدد
المجلد 5، العدد 1 (31 مارس/آذار 2021)، ص ص. 72-82، 11ص.
الناشر
تاريخ النشر
2021-03-31
دولة النشر
فلسطين (قطاع غزة)
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
The main objective: Link the incidence of the Toxoplasma gondii present and manifestations of some sex hormones at infertile persons.
Follicle-stimulating hormone (FSH), 17-β Estradiol (E2), and testosterone are key regulators for the development and progress of germline cells.
Also affect many defensive functions to the immune system.
Toxoplasma gondii attempts to manipulating these Hormones concentration to their survive.
The study methodology : since October 2018 tell 31th March 2019, 100 samples of the blood of infertile patients have been collected from both sexes from outpatient clinics in different areas of Qadisiyah governorate, Iraq.
All there examined with Elisa test to detect IgM and IgG antibodies against T.
gondii and to estimate concentration of sex hormones.
Results: 39 samples (39 %) were positive to T.
gondii.
IgM positive samples were (6 and 10) with (12% and 20%) at male and female, Positive IgG samples for male and female were (10 and 13) with (20% and 26%).
In male, Testosterone concentrations were increased in infected where were (5.4 and 5) ng/ ml with IgG and IgM test.
Also E2 were (33.6 and 35) pg/ ml with IgG and IgM infected men .
While FSH concentrations were decreased in (12.1 and 12.3) IU with IgG and IgM.
In female, FSH and E2 concentrations were increased in infected female, where were (5.45 and 5.9)IU/ ml and (260 and 250)pg/ ml from both hormones with IgG and IgM test.
Testosterone concentration was decreased (0.98)ng/ ml with IgG, but increased (1.35) ng/ ml with IgM in female.
The study has been showed that a significant difference in the concentrations of hormones studied between non-infected and infected samples in the acute case, and did not register a significant difference between chronic infection and non-infection, a significant increase in hormones Testosterone and E2 in male and female while FSH in female only, FSH concentration was lower in male after infection.
Conclusion: in light the study results the author see that: Infection with the parasite is associated with significant changes in the concentrations of sex hormones in infertile peoples, therefore it can be said that infection with Toxoplasma gondii is one of the main causes of infertility in both sexes.
Suggestions: Conduct broader studies by examining more people and determine the relationship between infertility and sex hormone concentration with infection by T.
gondii in girls and boys before or after puberty.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Aridi, Musafir Hindi Safar. 2021. The role of Toxoplasma gondii in concentration of some sex hormones in infertile individual. Journal of Medical and Pharmaceutical Sciences،Vol. 5, no. 1, pp.72-82.
https://search.emarefa.net/detail/BIM-1316339
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Aridi, Musafir Hindi Safar. The role of Toxoplasma gondii in concentration of some sex hormones in infertile individual. Journal of Medical and Pharmaceutical Sciences Vol. 5, no. 1 (Mar. 2021), pp.72-82.
https://search.emarefa.net/detail/BIM-1316339
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Aridi, Musafir Hindi Safar. The role of Toxoplasma gondii in concentration of some sex hormones in infertile individual. Journal of Medical and Pharmaceutical Sciences. 2021. Vol. 5, no. 1, pp.72-82.
https://search.emarefa.net/detail/BIM-1316339
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 79-82
رقم السجل
BIM-1316339
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر