A comparative study between transplantation of conjunctival limbal autograft with mitomycin c and amniotic membrane transplantation with mitomycin c in recurrent pterygium

الملخص EN

Introduction: Pterygium, a wing‐shaped encroachment of the cornea by the conjunctiva, Conjunctival limbal autograft with stem cell (CLAU) or amniotic membrane transplantation (AMT) has been widely adopted in the management of pterygium.

Purpose: To compare the efficacy and the complications of conjunctival limbal autograft (CLAU) with mitomycin C 0.2 % and amniotic membrane transplantation (AMT) with mitomycin C 0.2 % for treatment of recurrent pterygium Subject and methods: 80 eyes of 60 patients clinically diagnosed with recurrent pterygium were divided into two groups , group A included 40 eyes underwent pterygium excision and MMC 0.2% with CLAU , group B included 40 eyes underwent pterygium excision and MMC 0.2% with AMT .

Recurrence was defined as fibrovascular tissue extension of more than one mm onto the cornea in the area of previously excised pterygium.

Mean follow up period 8±1 month.

Recurrence was compared in each group by using ӽ2 test.

Results:No major postoperative complications occurred during 6-9 months of followup.

In CLAU group (A) only 5 eyes of recurrence occur (12.5%) after 7 months of follow up.

Recurrence occur in 12 eyes (30%) in AMT group (B) after 6 months (P value =0.043, ӽ2 test).The operated site was look like the normal adjacent site in 77%of the non-recurrence group A versus 10% in group B Conclusion: CLAU with MMC is more effective than AMT with MMC for treatment of recurrent pterygium and the final cosmetic appearance is more acceptable in CLAU group than AMT group B.