Macrophages derived from bovine monocyte subsets differently enhance the vitality of blood neutrophils in vitro
المؤلف
المصدر
Alexandria Journal of Veterinary Sciences
العدد
المجلد 57، العدد 1 (30 إبريل/نيسان 2018)، ص ص. 60-65، 6ص.
الناشر
جامعة الإسكندرية كلية الطب البيطري
تاريخ النشر
2018-04-30
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Recent studies have shown that bovine blood monocytes represent a heterogeneous population of circulating cells with distinct phenotypic and functional properties.
However, little is known about the heterogeneity of macrophages derived from different monocyte subsets.
The current study aimed at investigating the functional heterogeneity of macrophages derived from the three bovine monocyte subsets regarding their capacity to influence the vitality of bovine blood neutrophils.
Blood neutrophils were stimulated with culture supernatants from LPS-stimulated macrophages generated from different monocyte subsets.
Vitality of stimulated neutrophils was analyzed by flow cytometry using the mitochondrial membrane potential probe JC-1.
Similar to LPS, supernatant of stimulated monocyte-derived macrophages enhanced the life-span of neutrophils by reducing the percentages of apoptotic cells.
The comparison between macrophages derived from different monocyte subsets showed that culture supernatants of macrophages derived from classical and intermediate monocytes induced the strongest anti-apoptotic effect on neutrophils.
This suggests a role for macrophages derived from classical and intermediate monocytes rather than non-classical monocytes in prolonging the lifespan of neutrophils and therefore their contribution to innate immune defense during the acute phase of infection or inflammation.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Husayn, Jamal Ahmad. 2018. Macrophages derived from bovine monocyte subsets differently enhance the vitality of blood neutrophils in vitro. Alexandria Journal of Veterinary Sciences،Vol. 57, no. 1, pp.60-65.
https://search.emarefa.net/detail/BIM-1327853
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Husayn, Jamal Ahmad. Macrophages derived from bovine monocyte subsets differently enhance the vitality of blood neutrophils in vitro. Alexandria Journal of Veterinary Sciences Vol. 57, no. 1 (Apr. 2018), pp.60-65.
https://search.emarefa.net/detail/BIM-1327853
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Husayn, Jamal Ahmad. Macrophages derived from bovine monocyte subsets differently enhance the vitality of blood neutrophils in vitro. Alexandria Journal of Veterinary Sciences. 2018. Vol. 57, no. 1, pp.60-65.
https://search.emarefa.net/detail/BIM-1327853
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 64-65
رقم السجل
BIM-1327853
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر