Neuroleptic administration and eye changes in Jordanians

الملخص EN

Objectives : To investigate the effects of neuroleptics on the eyes.

Methods : The eyes of 88 Jordanian patients (50 males, 38 females) receiving neuroleptics were examined and compared to a control group of 73 subjects of similar age and sex distribution who had never taken neuroleptics.

The duration of treatment with neuroleptics was 24 months or longer.

Results : About 68.2 % of those taking neuroleptics showed ocular pigmentation compared to only 15 % of the control group ; a difference which was statistically significant Pigmentation affected the conjunctiva in 73 % of them.

Conclusion : Patients receiving neuroleptics showed ocular pigmentation.

Prevalence increased with the age of the patient, higher total dosage of neuroleptics and was greater in males than in females.