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Multiple drug resistant urinary tract infection in kidney transplant recipients : a retrospective cohort study
المؤلفون المشاركون
Khan, Muhammad Tasadduq
Ibn Hamid, Rashid
Lal, Naranjan
Sarfaraz, Sabahat
Javaid, Shanila
Luxmi, Shubha
المصدر
Saudi Journal of Kidney Diseases and Transplantation
العدد
المجلد 31، العدد 5 (31 أكتوبر/تشرين الأول 2020)، ص ص. 905-916، 12ص.
الناشر
تاريخ النشر
2020-10-31
دولة النشر
السعودية
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
Urinary tract infection (UTI) is the most common infectious disease in post-kidney transplantation patients.
The objective of the study was to investigate the prevalence, impact and risk factors of multiple drug resistant (MDR) UTI in kidney transplant recipients.
This retrospective cohort study recruited 72 kidney transplant recipients between March 2017 and February 2018.
Urine cultures performed during the 1st year of posttransplantation with reference to clinical data were evaluated.
Predesigned questionnaire was used to collect data regarding demographic, transplant related, and microbiological information.
Multivariate analysis was performed to ascertain risk factors of MDR UTI.
Out of 72 patients, 28 (38.9%) had culture guided clinical UTI.
Overall, 59 UTI episodes were noted throughout the duration of this study.
Eschericia coli were found to be the most frequent uropathogen of UTI among kidney transplant recipients (n = 32, 54.2%).
MDR bacteria were responsible for 27.1% (n = 16) of the post-transplantation UTI episodes among patients, with E.
coli (n = 9, 56.3%) being the predominant bacterial pathogen.
Most of the MDR strains of E.
coli (n = 7, 77.8%) were extended spectrum beta-lactamase positive.
Female gender (P <0.001), prolonged Foley's catheterization (P = 0.002), coexisting diabetes mellitus (DM) (P <0.001) and induction of anti-thymocyte globulin (ATG) therapy (P <0.001) were independently associated with high risk of MDR UTI.
The allograft rejection was found to be significantly higher in patients of posttransplantation UTI with MDR uropathogen (P = 0.009).
In conclusion, E.
coli were the most prominent uropathogen of UTI with and without MDR pathogen in the present study.
Female gender, prolonged Foley's catheterization, coexisting DM, and induction of ATG therapy were the risk factors independently associated with MDR UTI in kidney transplant recipients.
MDR organisms were significantly associated with allograft rejection.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ibn Hamid, Rashid& Javaid, Shanila& Khan, Muhammad Tasadduq& Lal, Naranjan& Luxmi, Shubha& Sarfaraz, Sabahat. 2020. Multiple drug resistant urinary tract infection in kidney transplant recipients : a retrospective cohort study. Saudi Journal of Kidney Diseases and Transplantation،Vol. 31, no. 5, pp.905-916.
https://search.emarefa.net/detail/BIM-1331669
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ibn Hamid, Rashid…[et al.]. Multiple drug resistant urinary tract infection in kidney transplant recipients : a retrospective cohort study. Saudi Journal of Kidney Diseases and Transplantation Vol. 31, no. 5 (Sep. / Oct. 2020), pp.905-916.
https://search.emarefa.net/detail/BIM-1331669
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ibn Hamid, Rashid& Javaid, Shanila& Khan, Muhammad Tasadduq& Lal, Naranjan& Luxmi, Shubha& Sarfaraz, Sabahat. Multiple drug resistant urinary tract infection in kidney transplant recipients : a retrospective cohort study. Saudi Journal of Kidney Diseases and Transplantation. 2020. Vol. 31, no. 5, pp.905-916.
https://search.emarefa.net/detail/BIM-1331669
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 914-916
رقم السجل
BIM-1331669
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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