Clinicopathological features and five-year survival of invasive non- metastatic breast cancer patients surgically treated in a single breast unit in Jordan in 2013
المؤلفون المشاركون
Nahar, Lina
al-Suudi, Majdi A.
Abu Rumman, Anas
Qasaymah, Hamzah
Abu Aysh, Umar
المصدر
Journal of the Royal Medical Services
العدد
المجلد 28، العدد 2 (31 أغسطس/آب 2021)، ص ص. 22-33، 12ص.
الناشر
الخدمات الطبية الملكية الأردنية
تاريخ النشر
2021-08-31
دولة النشر
الأردن
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
Background : breast cancer is still the most common cancer in females worldwide.
in 2013, the number of female breast cancer cases in Jordan was 1040 (36.5% of all female cancers)1.
studying survival and clinico-pathological features will provide an objective assessment about tumour biology in our region and specific treatment outcomes.
Objective : to assess the five-year survival of breast cancer patients who were treated at our breast unit, to evaluate clinicopathlogical features and correlate them with molecular subtypes.
materials and methods : a retrospective study that revised the histopathology reports of 129 breast cancer patients surgically treated at al-Hussein hospital from January 2013 until January 2014.
the patients were followed up till 2019 to assess their 5 year survival, clinicopathological features and molecular subtypes.
Results : the most common age group was 40–60 years (51.16%).
eighty six (66.67%) patients had axillary ln involvement.
most of the tumours were reported to be between 2 and 5 cm (t2) in 82 (63.57%) patients.
one hundred and fifteen (89.15%) patients had invasive ductal carcinoma (idc) nonspecific type.
grade 3 tumours were reported in 64 (49.61%) patients.
the tumours in 105 (81.40%) patients were er positive, those in 94 (72.87%) patients were pr positive and those in 96 (74.42%) patients were her2 receptor negative.
luminal a subtype was observed in 86 (66.6%) patients, followed by luminal b subtype in 21 (16.28%) then her2 enriched subtype in 12 (9.30%) and least in triple negative subtype in 10 (7.75%) patients.
there were nine (6.98%) patients who had stage 1, 58(44.96%) patients had stage 2 and 62 (46.06%) patients who had stage 3.
the five year survival according to stage was 100%, 87.93%, 69.35% for stages 1, 2 and 3 respectively.
conclusion : approximately half of the patients presented in the middle age group with relatively large tumour sizes and involved lymph nodes.
however, the majority of patients had a favourable molecular subtype (luminal a) accounting for why the 5-year survival for stage 3 was around 70%, which is relatively good and is comparable to worldwide results.
there was also a significant relationship (p = 0.022) between molecular subtypes and age groups used in the study warranting larger scale studies.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Suudi, Majdi A.& Abu Rumman, Anas& Qasaymah, Hamzah& Nahar, Lina& Abu Aysh, Umar. 2021. Clinicopathological features and five-year survival of invasive non- metastatic breast cancer patients surgically treated in a single breast unit in Jordan in 2013. Journal of the Royal Medical Services،Vol. 28, no. 2, pp.22-33.
https://search.emarefa.net/detail/BIM-1332625
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Suudi, Majdi A.…[et al.]. Clinicopathological features and five-year survival of invasive non- metastatic breast cancer patients surgically treated in a single breast unit in Jordan in 2013. Journal of the Royal Medical Services Vol. 28, no. 2 (Aug. 2021), pp.22-33.
https://search.emarefa.net/detail/BIM-1332625
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Suudi, Majdi A.& Abu Rumman, Anas& Qasaymah, Hamzah& Nahar, Lina& Abu Aysh, Umar. Clinicopathological features and five-year survival of invasive non- metastatic breast cancer patients surgically treated in a single breast unit in Jordan in 2013. Journal of the Royal Medical Services. 2021. Vol. 28, no. 2, pp.22-33.
https://search.emarefa.net/detail/BIM-1332625
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 32-33
رقم السجل
BIM-1332625
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر