Comparative between the effectiveness of different approaches for the treatment of bipolar disorder (pharmacological and psychological)‎ : results of a systematic review meta-analysis

الملخص EN

This research is a systematic review of the available data concerning the psychological and pharmacological treatment of bipolar disorder (BD), the aim of this review was to compare the effectiveness of psychotherapy and pharmacotherapy for bipolar disorder, it yielded 1620 publications between 2005 to 2020.

about 482 articles were repeated in more than one database.

also, we excluded 520 articles that did not assess the BD interventions.

then 579 articles were excluded because they were not a trial study.

finally, the remaining 19 articles were included in this systematic review that met inclusion criteria, the literature suggests that the pharmacological intervention (Quetiapine) is the most effective pharmacological intervention in the treatment of BD, and that the psychological intervention (cognitive behavioral therapy (CBT)) is the most effective psychological intervention in the treatment of bipolar disorder, also noted that the pharmacological intervention (probiotics) is the least effective pharmacological intervention in the treatment of BD and that the psychological intervention (anxiety intervention to individuals with BD (AIBD)) is the least effective psychological intervention in the treatment of bipolar disorder.