Adverse drug events in puppies following treatment with amoxicillin with or without clavulanate
المؤلفون المشاركون
Omobowale, Temidayo O.
Gberindyer, Fidelis A.
Shima, Felix K.
Omotosho, Oladipo O.
Abatan, Matthew O.
المصدر
Alexandria Journal of Veterinary Sciences
العدد
المجلد 59، العدد 1 (31 أكتوبر/تشرين الأول 2018)، ص ص. 143-148، 6ص.
الناشر
جامعة الإسكندرية كلية الطب البيطري
تاريخ النشر
2018-10-31
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
This study reports adverse drug events (ADEs) in puppies following treatment with amoxicillin with or without clavulanate.
a prospective and observational multicentre study was conducted in five Veterinary clinics in Nigeria where 63 heterogeneous puppies with parvovirus enteritis were used.
puppies in group A (n=36) were treated with amoxicillin alone (n=16), or with clavulanate (n=20) by IV route, whereas group B (n=27) were administered amoxicillin alone by IM route.
all puppies were administered a single dose of 15mg/kg, thereafter, observed for ADEs within 3 hours.
Those that manifested ADEs were subsequently administered 2mg/kg IV single dose of diphenhydramine.
Out of 63 puppies, 12(18.5%) had diarrhoea, hyper-salivation, cutaneous erythema, and swellings around eyelids and buccal areas within 5 minutes post-treatment.
these were observed only in puppies treated by IV route, where 5/16(31.3%) of those administered amoxicillin with clavulanate, and 7/20(35%) of those treated with amoxicillin alone showed these signs, which resolved following diphenhydramine administration.
No ADEs were observed after subsequent treatment of the affected puppies with amoxicillin alone by IM route.
although amoxicillin is usually well tolerated, this study recommends that veterinarians should be cautious when it becomes necessary to treat dogs with amoxicillin alone or with clavulanate by IV route to circumvent these ADEs.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Gberindyer, Fidelis A.& Shima, Felix K.& Omotosho, Oladipo O.& Omobowale, Temidayo O.& Abatan, Matthew O.. 2018. Adverse drug events in puppies following treatment with amoxicillin with or without clavulanate. Alexandria Journal of Veterinary Sciences،Vol. 59, no. 1, pp.143-148.
https://search.emarefa.net/detail/BIM-1340800
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Gberindyer, Fidelis A.…[et al.]. Adverse drug events in puppies following treatment with amoxicillin with or without clavulanate. Alexandria Journal of Veterinary Sciences Vol. 59, no. 1 (Oct. 2018), pp.143-148.
https://search.emarefa.net/detail/BIM-1340800
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Gberindyer, Fidelis A.& Shima, Felix K.& Omotosho, Oladipo O.& Omobowale, Temidayo O.& Abatan, Matthew O.. Adverse drug events in puppies following treatment with amoxicillin with or without clavulanate. Alexandria Journal of Veterinary Sciences. 2018. Vol. 59, no. 1, pp.143-148.
https://search.emarefa.net/detail/BIM-1340800
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 147-148
رقم السجل
BIM-1340800
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر