In silico taste-toxicological study of chlorfenvinphos, dichlofluanid, fonofos, or methacrifos partial degradation products
المؤلف
al-Ubaydi, Kafa Khalaf Hammud Muhammad
المصدر
Iraqi Journal of Industrial Research
العدد
المجلد 8، العدد 3 (31 ديسمبر/كانون الأول 2021)، ص ص. 127-135، 9ص.
الناشر
وزارة الصناعة و المعادن هيئة البحث و التطوير الصناعي
تاريخ النشر
2021-12-31
دولة النشر
العراق
عدد الصفحات
9
التخصصات الرئيسية
الموضوعات
الملخص EN
Toxicity is important factor to human and environment and can be tested in lab and by computerized models.
ProTox-II is in Silico method to assess safety of chemicals to minimize risk health threating to human and other living organisms in nature.
Taste of material is another character can be calculated in Silico model like virtualtaste.
Here, first attempt of using two computerized methods and hypothetical partial degradation products of four toxics materials used to control agricultural productivity was carried out to predicate taste and toxicity characters.
LD50, Toxicity Class, organ and end point toxicities, Tox21-Nuclear receptor signaling and stress response pathways of Chlorfenvinphos, Dichlofluanid, Fonofos, and Methacrifos with their hypothetical degradation products were calculated.
Hypothetical degradation products were a results of (C-C, C-O, C-N, C-S, C-P, P-O, P-S, or N-S) bond breakage.
The hypothesized degradation chemicals showed that most of them were with sour taste and their toxicity were less class compared to the parent compound but not to non-toxic material (Class 6, LD50 more than 5000 mg/kg).
Also, they were structurally toxics and could be interact with molecular cellular target resulting than parent compound if they presented in required Toxicity is important factor to human and environment and can be tested in lab and by computerized models.
ProTox-II is in Silico method to assess safety of chemicals to minimize risk health threating to human and other living organisms in nature.
Taste of material is another character can be calculated in Silico model like virtualtaste.
Here, first attempt of using two computerized methods and hypothetical partial degradation products of four toxics materials used to control agricultural productivity was carried out to predicate taste and toxicity characters.
LD50, Toxicity Class, organ and end point toxicities, Tox21-Nuclear receptor signaling and stress response pathways of Chlorfenvinphos, Dichlofluanid, Fonofos, and Methacrifos with their hypothetical degradation products were calculated.
Hypothetical degradation products were a results of (C-C, C-O, C-N, C-S, C-P, P-O, P-S, or N-S) bond breakage.
The hypothesized degradation chemicals showed that most of them were with sour taste and their toxicity were less class compared to the parent compound but not to non-toxic material (Class 6, LD50 more than 5000 mg/kg).
Also, they were structurally toxics and could be interact with molecular cellular target resulting than parent compound if they presented in required concentration.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Ubaydi, Kafa Khalaf Hammud Muhammad. 2021. In silico taste-toxicological study of chlorfenvinphos, dichlofluanid, fonofos, or methacrifos partial degradation products. Iraqi Journal of Industrial Research،Vol. 8, no. 3, pp.127-135.
https://search.emarefa.net/detail/BIM-1366650
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Ubaydi, Kafa Khalaf Hammud Muhammad. In silico taste-toxicological study of chlorfenvinphos, dichlofluanid, fonofos, or methacrifos partial degradation products. Iraqi Journal of Industrial Research Vol. 8, no. 3 (2021), pp.127-135.
https://search.emarefa.net/detail/BIM-1366650
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Ubaydi, Kafa Khalaf Hammud Muhammad. In silico taste-toxicological study of chlorfenvinphos, dichlofluanid, fonofos, or methacrifos partial degradation products. Iraqi Journal of Industrial Research. 2021. Vol. 8, no. 3, pp.127-135.
https://search.emarefa.net/detail/BIM-1366650
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 134-136
رقم السجل
BIM-1366650
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر