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The clinical outcome of intravenous single bolus 0.5 gm of tranexamic acid for reducing blood loss following an elective cesarean delivery : a randomized controlled trial
المؤلفون المشاركون
Shadi, Nahlah W.
Salam, Hani F.
المصدر
Suez Canal University Medical Journal
العدد
المجلد 25، العدد 1 (31 مارس/آذار 2022)، ص ص. 125-134، 10ص.
الناشر
تاريخ النشر
2022-03-31
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الموضوعات
الملخص EN
Objective : to assess the effectiveness and safety of intravenous single bolus 0.5 gm tranexamic acid (TA), compared with 1 gm ta and placebo in reducing blood loss during and after cesarean delivery in women who have at least one risk factor for postpartum hemorrhage (PPH).
subjects and methods : a randomized clinical trial, at a tertiary university hospital between November 1, 2018, and July 30, 2020, ( : NCT 03710330) was conducted on 360 pregnant women at term (37–40 weeks) gestation scheduled for elective cesarean delivery, who were assigned to either 0.5 gm, 1 gm, or, placebo (saline).
the main outcome measures were blood loss at and 6 hours after cesarean delivery, the need for any additional oxytocic drugs, and ta-related side effects.
results : the mean overall blood loss was (609.33 ± 211.5), intraoperative was (465.58 ± 191) and post-operative was (143.75 ± 33.33) in group 2 compared with (829.7 ± 293.3), (665.5 ± 272.2), (165.83 ± 36.59) in group 1 respectively and (751 ± 208.09), (587.75 ± 190.6), (164.08 ± 32.53) in group 3 respectively , so group 2 showed great significant reduction in overall estimated blood loss either intraoperative or post-operative compared with group 1, (p = 0.0001,0.0001,0.0001) and group 3, (p = 0.0001,0.0001,0.0001).
conclusion : both 0.5 gm and 1 gm ta may be more effective than a placebo in reducing total blood loss during and after cd, but 1 gm ta may be more effective than 0,5 gm ta in reducing blood loss during and after cd in women who have a minimum of one risk factor for postpartum hemorrhage, for instance, twin pregnancy, macrosomia, and history of PPH, etc.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Shadi, Nahlah W.& Salam, Hani F.. 2022. The clinical outcome of intravenous single bolus 0.5 gm of tranexamic acid for reducing blood loss following an elective cesarean delivery : a randomized controlled trial. Suez Canal University Medical Journal،Vol. 25, no. 1, pp.125-134.
https://search.emarefa.net/detail/BIM-1374792
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Shadi, Nahlah W.& Salam, Hani F.. The clinical outcome of intravenous single bolus 0.5 gm of tranexamic acid for reducing blood loss following an elective cesarean delivery : a randomized controlled trial. Suez Canal University Medical Journal Vol. 25, no. 1 (2022), pp.125-134.
https://search.emarefa.net/detail/BIM-1374792
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Shadi, Nahlah W.& Salam, Hani F.. The clinical outcome of intravenous single bolus 0.5 gm of tranexamic acid for reducing blood loss following an elective cesarean delivery : a randomized controlled trial. Suez Canal University Medical Journal. 2022. Vol. 25, no. 1, pp.125-134.
https://search.emarefa.net/detail/BIM-1374792
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 132-134
رقم السجل
BIM-1374792
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
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