![](/images/graphics-bg.png)
Hepcidin status among iron deficient anemic pregnant women in Gaza strip : a case control study
المؤلفون المشاركون
al-Nabahin, Isra Muhammad Ilayyan
al-Zaharnah, MazIn
al-Zabut, Bakr Muhammad
المصدر
IUG Journal of Natural Studies
العدد
المجلد 29، العدد 1 (30 يونيو/حزيران 2021)، ص ص. 26-37، 12ص.
الناشر
الجامعة الإسلامية-غزة عمادة شؤون البحث العلمي و الدراسات العليا
تاريخ النشر
2021-06-30
دولة النشر
فلسطين (قطاع غزة)
عدد الصفحات
12
التخصصات الرئيسية
العلوم الطبيعية والحياتية (متداخلة التخصصات)
الملخص EN
Background: Hepcidin, a peptide hormone composed of 25 amino acids.
Hepcidin is synthesized mainly in the liver.
Iron deficiency anemia (IDA) is common during pregnancy and is associated with higher maternal morbidity and mortality in Gaza strip.
Understanding of hepcidin hormone and its role in iron metabolism could lead to a new sensitive indicator for earlier detection of cases with IDA.
Objective: To assess hepcidin status among IDA pregnant women and its relationship with some biochemical variables in Gaza strip.
Materials and methods: A case control study comprised 45 IDA pregnant women and 45 apparently healthy pregnant women.
Questionnaire interviews were applied among the study population.
Serum hepcidin and ferritin were measured by Enzyme-linked immunosorbent assay (ELISA), iron and total iron binding capacity (TIBC) were determined photometrically.
Complete blood count (CBC) was also performed.
Transferrin and transferrin saturation were calculated.
An approval was obtained from Helsinki committee and ministry of health to conduct this study.
Overall data were computer analyzed using SPSS (Ver.
18).
Results: The mean levels of serum hepcidin, iron, transferrin saturation, and ferritin in cases were significantly lower compared to those of controls (2.6±4 ng/ml, 63.2±25.3 μg/dl, 15.6±8.0% and 8.0±9.7 ng/ml versus 7.5±7.3 ng/ml, 77.7±22.9 μg/dl, 23.5±8.0% and 15.4±14.3 ng/ml respectively with P=0.000).
The Pearson correlation test showed that positive significant correlations between hepcidin levels and serum iron, ferritin, and transferrin saturation (P<0.001).
On the other hand, negative significant correlations were showed with TIBC and transferrin (P<0.001).
Conclusions: Serum hepcidin level has a relationship with anemia among pregnant women.
Therefore, monitoring of hepcidin levels can play an important role in management of anemia among pregnant women.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Nabahin, Isra Muhammad Ilayyan& al-Zaharnah, MazIn& al-Zabut, Bakr Muhammad. 2021. Hepcidin status among iron deficient anemic pregnant women in Gaza strip : a case control study. IUG Journal of Natural Studies،Vol. 29, no. 1, pp.26-37.
https://search.emarefa.net/detail/BIM-1380581
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Nabahin, Isra Muhammad Ilayyan…[et al.]. Hepcidin status among iron deficient anemic pregnant women in Gaza strip : a case control study. IUG Journal of Natural Studies Vol. 29, no. 1 (2021), pp.26-37.
https://search.emarefa.net/detail/BIM-1380581
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Nabahin, Isra Muhammad Ilayyan& al-Zaharnah, MazIn& al-Zabut, Bakr Muhammad. Hepcidin status among iron deficient anemic pregnant women in Gaza strip : a case control study. IUG Journal of Natural Studies. 2021. Vol. 29, no. 1, pp.26-37.
https://search.emarefa.net/detail/BIM-1380581
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 36-37
رقم السجل
BIM-1380581
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)