Investigate the relation between polymorphism of (CTLA-4)‎ gene and asthma in some patients at Thi-Qar province-Iraq

الملخص EN

The present study was carried out at the Biology Department laboratories, for the period of (December 2017 to November 2018).

The aim of the current study was to investigate polymorphism of CTLA-4 gene in patients with Asthma.

The study subject consisted of patients with asthma (74 females) and (26 males) were their aged between (15-55) years, with (50 persons as control group.

After DNA extraction, PCR was made by using specific primers for the CTLA-4 gene, the study results explained the incidence of polymorphisms in a samples of 25 out of asthma patients when using the restriction enzyme (BSTEII).

After analyzing the results by statistical analysis results showed that no association between the incidence of Asthma and appearance of mutation in CTLA-4 gene when compared to the control group.