Association of irisin hormone with some physiological and inflammatory parameters in patients with type 2 diabetic mellitus (T2DM) in Thi-Qar province-Iraq
المؤلفون المشاركون
al-Badri, Sad H.
al-Fartusi, Khalid G.
المصدر
Journal of College of Education for Pure Sciences
العدد
المجلد 10، العدد 1 (31 مارس/آذار 2020)، ص ص. 52-60، 9ص.
الناشر
جامعة ذي قار كلية التربية للعلوم الصرفة
تاريخ النشر
2020-03-31
دولة النشر
العراق
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
The present study aimed to assessment of irisin level in patients with the newly onset type 2 "diabetes mellitus" (T2D.M.) and the scanning the association of irisin value with some physiological and inflammatory parameters.
This study comprised 60 individuals diagnosed in newly onset T2D.M.
and 40 healthy contributors (control group).
IL-6 and C-reactive protein(CRP) concentration was calculated in patient who involved in this study.
Serum irisin levels in addition to inflammatory factors were evaluated by ELISA kit.
The present study showed a significant increasing (P ≤ 0.05) of glycohemoglobin (HbA1C) and FBS level in patient with DM2 compared with the control groups (6.88 ± 1.02 vs 4.15±0.56; 7.85 ± 1.89 vs 4.94 ± 0.40) respectively.
Also, the results explained a significant increased (P ≤ 0.05) of T-Ch, Tg and LDL level in DM2 group compared with the control group (4.27±0.90 vs 4.23± 0.40; 2.14 ± 0.86 vs 1.89 ± 0.26; 2.84 ± 0.94 vs 2.23 ± 0.52) respectively.
Whereas, the results showed a significant decrease (P ≤ 0.05) of irisin, insulin, C-peptide and HLD in DM2 group compared with the control group (22.32 ± 4.55 vs 27.81 ± 2.93; 18.29 ± 3.66 vs 27.27 ± 6.90; 3.12 ± 0.99 vs 6.03 ± 0.48; 1.0 ± 0.17 vs 1.61±0.37) respectively.
On the other hand, the results of inflammatory parameters showed a significant increase (P ≤ 0.05) of IL-6 and CRP level compared with the control group (19.85 ± 4.97 vs 12.0 ± 1.23; 8.41 ± 2.11 vs 4.60 ± 0.35) respectively.
In correlation analysis the results showed a negative association between irisin and (HbA1c) (r= -0.152), glucose (r= -0.331), insulin (r= -0.156), HDL (r= -0.114) and BMI (r= -0.219).
Whereas, the results showed positive correlation between irisin and IL-6 (r=0.
0.115), CRP (r= 0.153), C-peptide (r=0.013), T-Ch (r= 0.057), Tg (r=0.209) and LDL(r=0.035).
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Badri, Sad H.& al-Fartusi, Khalid G.. 2020. Association of irisin hormone with some physiological and inflammatory parameters in patients with type 2 diabetic mellitus (T2DM) in Thi-Qar province-Iraq. Journal of College of Education for Pure Sciences،Vol. 10, no. 1, pp.52-60.
https://search.emarefa.net/detail/BIM-1383753
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Badri, Sad H.& al-Fartusi, Khalid G.. Association of irisin hormone with some physiological and inflammatory parameters in patients with type 2 diabetic mellitus (T2DM) in Thi-Qar province-Iraq. Journal of College of Education for Pure Sciences Vol. 10, no. 1 (Mar. 2020), pp.52-60.
https://search.emarefa.net/detail/BIM-1383753
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Badri, Sad H.& al-Fartusi, Khalid G.. Association of irisin hormone with some physiological and inflammatory parameters in patients with type 2 diabetic mellitus (T2DM) in Thi-Qar province-Iraq. Journal of College of Education for Pure Sciences. 2020. Vol. 10, no. 1, pp.52-60.
https://search.emarefa.net/detail/BIM-1383753
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 58-60
رقم السجل
BIM-1383753
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر