Some bacteriological, hematological and biochemical changes on 107 clinical mastitis in goat

الملخص EN

This study included clinical examination of 120 goats bred in diffe localities of Dakahlia Governorate where 70% were clinically mastitfc The results of microscopical examination of 168 mastitic milk samples revealed that 73.8% were positive, 77.4% out of them gave pure sing]e cultures and 22.6% yielded mixed ones.

The bacteriological examination of positive samples yielded 124 isolates where Staphylococcus aureus Staph, epidermidis, E.

coli, Streptococcus agalactiae, Strept.

dysglactia'e and Strept.

uberis were the main organisms.

These strains were isolated at varying percentages 35.4%, 27.1%, 16.1%, 10.4%, 8.3% and 2.1% respectively.

Pathogenicity test in mice revealed that Staph, aureus and E.

coli were highly virulent strains.

The results of the invitro antimicrobial sensitivity test showed that Enrofloxacin, Ceftiofur Ciprofloxacin, Gentamycin and Lincomycin were the most effective antibiotics for successful treatment of mastitic goats.

Biochemical studies of blood serum samples of mastitic does were discussed in details and revealed on increase in the levels of total protein, Alpha 2, gamma globulin, but the level of albumin and A/G ratio were decreased significantly in their values.

Meanwhile studies of minerals profiles revealed that, the mean values of Ca, IP, Mg, K, Zn and Fe were decreased significantly, at the same time the level of Na and Cu values were increased significantly.

Some biochemical liver and kidney functions in the present studies were discussed and revealed a significant increased in the liver enzymes AST, ALT and also in the level of blood urea nitrogen and serum creatinine.

Hematological parameters of blood samples of mastitis does were also discussed in details and the studies revealed that, the mean values of Hb, TRBCs, TWBCs were decreased significantly.

At the same time,-the differential leucocytic count profiles revealed that the percentage of lymphocytes, neutrophils were decreased significantly, while the percentage of monocytes, eosinophils and basophiles were significantly increased