Study of the effect of adding topical Nepafenac 0.1% eye drop on increasing mydriasis in patients with diabetes mellitus type 2

العناوين الأخرى

دراسة فعالية إضافة قطرة النيبافيناك املوضعي 1.0 % في زيادة توسع الحدقة لدى مرض ى الداء السكري النمط 2

المؤلفون المشاركون

Sabbagh, Mishil Thamin
Jallul, Qahtan
Rajab, Mahmud

المصدر

Journal of Medical and Pharmaceutical Sciences

العدد

المجلد 6، العدد 1 (31 مارس/آذار 2022)، ص ص. 74-81، 8ص.

الناشر

المركز القومي للبحوث

تاريخ النشر

2022-03-31

دولة النشر

فلسطين (قطاع غزة)

عدد الصفحات

8

التخصصات الرئيسية

العلوم الطبية والصيدلة والعلوم الصحية

الملخص EN

Objective: To evaluate the effect of adding topical Nepafenac 0.1% eye drop on increasing mydriasis in patients with Diabetes Mellitus type 2.

Methods: the study was conducted on 73 eyes of 73 patients who had type 2 diabetes for 5 years or more.

The pupil diameter (PD) was measured in the both eyes without dilation using an Autorefractokeratometer (Grand Seiko\GR- 3500 Ka), then the pupils were dilated in the both eyes using topical Tropicamide 1%.

A second measurement of (PD) was taken after dilating using the same device.

Topical Nepafenac 0.1% were prescribed 3 times a day for 3 days in the right eye.

During the review, after 3 days, the pupils were dilated using topical Tropicamide 1%.

A third measurement of the (PD) of the both eyes was taken after dilation using the same device.

The efficacy of Nepafenac 0.1% was evaluated by determining the increase in (PD) in the eye that received topical Nepafenac 0.1% and comparing it with the other eye that did not receive.

Results: The mean diameter of the pupil in the right eye after dilation was 4.68±0.8 mm and in the left eye was 4.67±0.7 mm (P=0.8).

After applying Nepafenac 0.1% topically 3 times a day in the right eye for 3 days, the mean diameter of the pupil in the right eye after dilation was 6.50 ± 0.9 mm and in the left eye 5.10± 0.08 mm (P=0.001).

The change in the mean diameter of the pupil in the right eye was 1.82 ± 0.7 mm, and in the left eye was 0.43 ± 0.6 mm.

Conclusion: Topical application of Nepafenac 0.1% showed an increase in pupillary diameter after dilation with Tropicamide 1% in patients with type 2 diabetes mellitus.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Sabbagh, Mishil Thamin& Rajab, Mahmud& Jallul, Qahtan. 2022. Study of the effect of adding topical Nepafenac 0.1% eye drop on increasing mydriasis in patients with diabetes mellitus type 2. Journal of Medical and Pharmaceutical Sciences،Vol. 6, no. 1, pp.74-81.
https://search.emarefa.net/detail/BIM-1407716

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Sabbagh, Mishil Thamin…[et al.]. Study of the effect of adding topical Nepafenac 0.1% eye drop on increasing mydriasis in patients with diabetes mellitus type 2. Journal of Medical and Pharmaceutical Sciences Vol. 6, no. 1 (Mar. 2022), pp.74-81.
https://search.emarefa.net/detail/BIM-1407716

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Sabbagh, Mishil Thamin& Rajab, Mahmud& Jallul, Qahtan. Study of the effect of adding topical Nepafenac 0.1% eye drop on increasing mydriasis in patients with diabetes mellitus type 2. Journal of Medical and Pharmaceutical Sciences. 2022. Vol. 6, no. 1, pp.74-81.
https://search.emarefa.net/detail/BIM-1407716

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references : p. 80-81

رقم السجل

BIM-1407716