![](/images/graphics-bg.png)
Cardioprotective properties of natural medicine in isoproterenol induced myocardial damage in the male albino rats
المؤلف
Seshadri, Vidya Devanathadesikan
المصدر
Saudi Journal of Biological Sciences
العدد
المجلد 28، العدد 6 (30 يونيو/حزيران 2021)، ص ص. 3169-3175، 7ص.
الناشر
تاريخ النشر
2021-06-30
دولة النشر
السعودية
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
The main aim of this study is to investigate cardioprotective properties of natural medicine inmyocardial damage induced male albino rats.
the aqueous extractof allium sativumwas used for the determination of phenolic compounds and flavonoids.
the amount of phenol (1.39 ± 0.37 gae/g dry weight) and flavonoids(49.1 ± 2.79 qe/g dry weight) were high in aqueous extract.
a.
sativumextract and showed 68.39 ± 3.6% dpphscavenging activity.
isoproterenol was used to induce myocardial injury in albino rats in vivo by subcutaneous injection (100 mg/kg body weight).
to achieve this, experimental animals were categorized into six groups (n = 4), namely, positive, negative control, only isoproterenol administered groups, and garlic extract administered group at 100–300 mg extract/kg body weight.
oxidative stress marker and cardiac markers were assayed to analyze the cardioprotective properties of garlic extract.
at 300 mg/ kg doseof garlic extract, rat was recovered from various altered factors such as, aspartate aminotransferase, alkaline transminase and alkaline phosphatase.
the rats treated with 300 mggarlic extract/kg body weight decreased the level of asparate aminotransferase (126 ± 6.4 iu/l) than other lower doses (100 mg extract/kg and 200 mg extract/kg).
alkaline transaminase level of rat serum level was 81 ± 4.34 iu/l.
in the isoproterenol treated rats elevated level was observed (152 ± 4.42 iu/l enzyme activity).
pretreatment of albino rat with a.
sativum extract reduced cardiac damage.
isoproterenol exposed animal showed 207.6 ± 1.2 mg/dl triglyceride and the garlic administered rat (300 mgextract/kg) reduced ldl-cholesterol level (61.3 ± 1.3 mg/dl) significantly (p < 0.05).
creatinine kinase -mb level was 269.5± 12.5 iu/l in the control animal and stress induced animal showed elevated level (572.3 ± 19.4 iu/l).
garlic treated experimental animal (300 mg/kg bw) decreased ck-mb level.
to conclude, the aqueous extract of a.
sativumshowed cardio protective properties against myocardial injury.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Seshadri, Vidya Devanathadesikan. 2021. Cardioprotective properties of natural medicine in isoproterenol induced myocardial damage in the male albino rats. Saudi Journal of Biological Sciences،Vol. 28, no. 6, pp.3169-3175.
https://search.emarefa.net/detail/BIM-1407763
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Seshadri, Vidya Devanathadesikan. Cardioprotective properties of natural medicine in isoproterenol induced myocardial damage in the male albino rats. Saudi Journal of Biological Sciences Vol. 28, no. 6 (2021), pp.3169-3175.
https://search.emarefa.net/detail/BIM-1407763
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Seshadri, Vidya Devanathadesikan. Cardioprotective properties of natural medicine in isoproterenol induced myocardial damage in the male albino rats. Saudi Journal of Biological Sciences. 2021. Vol. 28, no. 6, pp.3169-3175.
https://search.emarefa.net/detail/BIM-1407763
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 3174-3175
رقم السجل
BIM-1407763
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)