Antimicrobial activity of essential oils from thyme and rosemary, and their potential uses as natural preservatives in pediatric pharmaceutical dosage forms

مقدم أطروحة جامعية

Abu Daqqah, Muhannad Khalil

مشرف أطروحة جامعية

Farraj, Muhammad
Shtaya, Hani

الجامعة

جامعة بيرزيت

الكلية

كلية العلوم

القسم الأكاديمي

دائرة الأحياء و الكيمياء الحيوية

دولة الجامعة

فلسطين (الضفة الغربية)

الدرجة العلمية

ماجستير

تاريخ الدرجة العلمية

2016

الملخص الإنجليزي

Antimicrobial preservatives are substances added to food and pharmaceutical products to inhibit the growth of microorganisms introduced during the manufacturing process or during usage and storage.

Antimicrobial agents may contain toxic substances.

Therefore, it is important to add the effective concentration of the preservatives to packaged products taking in consideration that it is below a level that may be toxic to humans.

Avoidance of pathogenic and spoilage microorganisms in pharmaceutical products, is usually achieved by using chemical preservatives.

However, these chemical preservatives are toxic.

The aim of the present study will assess the antimicrobial activities of thymol (C10H14O) is the main monoterpene phenol found in thyme essential oil, rosmarinic acid (C18H16O8) which is one of the most abundant individual active antioxidant components in rosemary, Coridothymus capitatus L.

and Rosmarinus officinalis L.

essential oils, and to compare their effectiveness against reference ATCC microorganisms.

The aim of the present study will assess the antimicrobial activities of thyme oil, rosemary oil, thymol, and rosmarinic acid, and to study their preservative effectiveness test against reference ATCC microorganisms, to compare their effectiveness with well-known chemical preservative and to evaluate their use as antimicrobial agents (preservatives) for different pharmaceutical preparations especially for pediatric preparations.

التخصصات الرئيسية

الأحياء

عدد الصفحات

76

قائمة المحتويات

• APA
• MLA
• AMA

لغة النص

الإنجليزية

نوع البيانات

رسائل جامعية

رقم السجل

BIM-1412749