Changes in clinicopathological characteristics of patients with idiopathic membranous nephropathy : a single-center retrospective study
المؤلفون المشاركون
Lou, Yan
Cui, Wenpeng
Guo, Qiaoyan
Nie, Ping
Luo, Ping
Zhang, Yixiang
Gao, Dan
المصدر
Iranian Red Crescent Medical Journal
العدد
المجلد 22، العدد 5 (31 مايو/أيار 2020)، ص ص. 1-6، 6ص.
الناشر
تاريخ النشر
2020-05-31
دولة النشر
الإمارات العربية المتحدة
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background: The prevalence of Idiopathic Membranous Nephropathy (IMN) among patients with Primary Glomerular Disease (PGD) has increased in China.
Objectives: This cross-sectional studyaimedto investigate changes in the clinicopathological features associated withIMNin northeast China.
Methods:We analyzed clinical and pathological data of 1,198 patients with IMN among 4,083 patients hospitalized with PGD undergoing renal biopsy from January 1, 2005, to December 31, 2018 at the Second Hospital of Jilin University in northeast China.
Enrollees were divided into two groups: those seen from 2005 to 2011 (Group 1) and those seen from 2012 to 2018 (Group 2).
We compared the clinicopathological features between Group 1 and Group 2.
Results: The percentage of patients with IMN among those with PGD increased over the 14 years of the study (P = 0.001).
The maleto- female ratio, prevalence of microscopic hematuria, and proteinuria levels were higher in Group 2 than in Group 1 (P < 0.05).
Among those with PGD, the percentages of patients with IMN-total, IMN-I, IMN-II, and IMN-III+IV, as well as Tubulointerstitial Lesion (TIL) scores, were higher in Group 2 than in Group 1 (P < 0.05).
Finally, age (P < 0.001), degree of proteinuria (P < 0.001), and serum triglyceride level (P = 0.027) were significantly associated with TIL scores among patients with IMN.
Conclusions: Membranous nephropathy is now the leading cause of PGD, with increased TIL scores during the study period.
Advanced age, high proteinuria, and serum triglyceride levels represent the independent risk factors for severe TIL among patients with IMN.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Lou, Yan& Gao, Dan& Guo, Qiaoyan& Zhang, Yixiang& Nie, Ping& Luo, Ping…[et al.]. 2020. Changes in clinicopathological characteristics of patients with idiopathic membranous nephropathy : a single-center retrospective study. Iranian Red Crescent Medical Journal،Vol. 22, no. 5, pp.1-6.
https://search.emarefa.net/detail/BIM-1430569
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Lou, Yan…[et al.]. Changes in clinicopathological characteristics of patients with idiopathic membranous nephropathy : a single-center retrospective study. Iranian Red Crescent Medical Journal Vol. 22, no. 5 (May. 2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1430569
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Lou, Yan& Gao, Dan& Guo, Qiaoyan& Zhang, Yixiang& Nie, Ping& Luo, Ping…[et al.]. Changes in clinicopathological characteristics of patients with idiopathic membranous nephropathy : a single-center retrospective study. Iranian Red Crescent Medical Journal. 2020. Vol. 22, no. 5, pp.1-6.
https://search.emarefa.net/detail/BIM-1430569
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 6
رقم السجل
BIM-1430569
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر