Detection of Serum Biochemical Markers in Elderly Patients with Type 2 Diabetes Mellitus and Its Relationship with Coronary Heart Disease
المؤلفون المشاركون
Zhang, Junran
Ma, Qinghua
Shao, Kaiyan
Yang, Shuguo
المصدر
Iranian Red Crescent Medical Journal
العدد
المجلد 22، العدد 8 (31 أغسطس/آب 2020)، ص ص. 1-6، 6ص.
الناشر
تاريخ النشر
2020-08-31
دولة النشر
الإمارات العربية المتحدة
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background: Coronary heart disease (CHD) is myocardial ischemia caused by coronary atherosclerosis and stenosis.
Objectives: This study aimed to investigate the relationship of CHD with glycated albumin (GA), glycosylated hemoglobin (HbA 1c), glucose (Glu), homocysteine (Hcy), triglyceride (TG), and apolipop protein A (apoA) levels in elderly patients with type 2 diabetes mellitus (T2DM).
Moreover, it was attempted to predict which changes had a significant correlation with the occurrence of CHD in these biochemical indicators.
Methods: This clinical cohort study included a total of 472 patients admitted to our hospital from June 2018 to June 2019.
They were then divided into three groups of concurrent (n=168, T2DM complicated with CHD), DM (n=148, T2DM alone), and control (n=156, healthy individuals).
Results: There were significant differences between the disease group (i.e., DM and concurrent groups) and control group in terms of GA (P=0.013, 28.58±8.01 vs.
15.77±1.44), HbA 1c (P=0.022, 9.5±1.5 vs.
5.5±0.5), Glu (P=0.012, 8.54±2.23 vs.
4.12±0.39), Hcy (P=0.031, 11.16±3.28 vs.
5.03±2.87), TG (P=0.021, 1.83±0.49 vs.
0.84±0.18), and apoA (P=0.031, 1.10±0.12 vs.
1.30±0.18).
Moreover, GA (P=0.025, 27.14±6.34 vs.
28.58±8.01; concurrent group vs.
DM group), HbA 1c (P=0.033, 8.3±1.2 vs.
9.5±1.5; concurrent group vs.
DM group), Glu (P=0.019, 8.62±3.56 vs.
8.54±2.23; concurrent group vs.
DM group), Hcy (P=0.031, 17.56±6.36 vs.
11.16±3.28; concurrent group vs.
DM group), total cholesterol ([TC); P=0.022, 3.06±0.20 vs.
3.69±0.29; concurrent group vs.
DM group), and low-density lipoprotein ([LDL); P=0.037, 2.57±1.02 vs.
3.40±1.17; concurrent group vs.
DM group) in disease group (DM group and concurrent group) were higher than those in the control group; however, apoA (P=0.023, 0.95±0.12 vs.
1.10±0.12; concurrent group vs.
DM group) in disease group was lower than that in the control group.
Furthermore, there were significant differences between the disease and control groups in terms of GA, HbA 1c, Glu, Hcy, TC, LDL, and apoA (P <0.05) Pearson correlation analysis between DM and concurrent groups was performed on the clinical parameters with statistical differences, and GA was highly correlated with HbA 1c and Glu (P<0.01> Conclusion: High-risk patient screening with high levels of GA, Hcy, and apoA in elderly patients with T2DM can not only improve the symptoms of patients with targeted treatment but also reduce the incidence of CHD by timely intervention, which is of great significance to improve the quality of life of patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zhang, Junran& Shao, Kaiyan& Yang, Shuguo& Ma, Qinghua. 2020. Detection of Serum Biochemical Markers in Elderly Patients with Type 2 Diabetes Mellitus and Its Relationship with Coronary Heart Disease. Iranian Red Crescent Medical Journal،Vol. 22, no. 8, pp.1-6.
https://search.emarefa.net/detail/BIM-1431429
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zhang, Junran…[et al.]. Detection of Serum Biochemical Markers in Elderly Patients with Type 2 Diabetes Mellitus and Its Relationship with Coronary Heart Disease. Iranian Red Crescent Medical Journal Vol. 22, no. 8 (Aug. 2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1431429
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zhang, Junran& Shao, Kaiyan& Yang, Shuguo& Ma, Qinghua. Detection of Serum Biochemical Markers in Elderly Patients with Type 2 Diabetes Mellitus and Its Relationship with Coronary Heart Disease. Iranian Red Crescent Medical Journal. 2020. Vol. 22, no. 8, pp.1-6.
https://search.emarefa.net/detail/BIM-1431429
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 5-6
رقم السجل
BIM-1431429
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر