Demographics, serology and vitamin D status in Jordanians with coeliac disease
المؤلفون المشاركون
al-Sharari, Dayf Allah
Khasawinah, Hayah
Ugeilat, Tania
al-Zughul, Arin
al-Sukhani, Halah
Quran, Asma
Kasawniah, Rami
المصدر
Journal of the Royal Medical Services
العدد
المجلد 29، العدد 1 (30 إبريل/نيسان 2022)، ص ص. 22-27، 6ص.
الناشر
الخدمات الطبية الملكية الأردنية
تاريخ النشر
2022-04-30
دولة النشر
الأردن
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background : Coeliac disease (CD) is an immune-mediated enteropathy that causes intestinal villous atrophy and malabsorption.
One of the malabsorbed micronutrients is vitamin D.
Objective : This retrospective study analysed epidemiological aspects of Jordanian CD patients, their serum vitamin D levels and anti-tissue transglutaminase (tTG) IgA and IgG antibody levels at King Hussein Medical Centre.
Methods : In this retrospective analysis we identified 116 biopsy-proven CD patients between 2016 and 2019.
The computerized patient record system was the referral source for the following clinical and laboratory parameters: age, gender, presenting symptoms, serum 25-hydroxyvitamin D3 level and anti-tTG IgA and IgG antibody levels.
Data were analysed with SPSS version 26 software for statistical significance using the Mann-Whitney U test; a p value of < 0.05 was considered to be significant.
Results : 116 CD patients showed female predominance, with a female/male ratio of 1.8:1, and an age range of 3–78 years.
Seventeen patients (15%) were asymptomatic.
Positive serum tTG IgA or IgG antibodies, or both, were found in 81 patients (69.8%).
Sixty patients (51.73%) were vitamin D deficient, 41 (35.33%) were insufficient and 15 (12.93%) had sufficient levels.
No correlation was found between any parameters apart from a positive correlation between tTG IgA and IgG antibodies (p = 0.009).
Conclusion : Vitamin D deficiency is common in CD patients and should be ruled out regardless of age, presenting symptoms or anti-tTG antibody status.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Sharari, Dayf Allah& Khasawinah, Hayah& al-Zughul, Arin& al-Sukhani, Halah& Quran, Asma& Kasawniah, Rami…[et al.]. 2022. Demographics, serology and vitamin D status in Jordanians with coeliac disease. Journal of the Royal Medical Services،Vol. 29, no. 1, pp.22-27.
https://search.emarefa.net/detail/BIM-1435374
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Sharari, Dayf Allah…[et al.]. Demographics, serology and vitamin D status in Jordanians with coeliac disease. Journal of the Royal Medical Services Vol. 29, no. 1 (Apr. 2022), pp.22-27.
https://search.emarefa.net/detail/BIM-1435374
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Sharari, Dayf Allah& Khasawinah, Hayah& al-Zughul, Arin& al-Sukhani, Halah& Quran, Asma& Kasawniah, Rami…[et al.]. Demographics, serology and vitamin D status in Jordanians with coeliac disease. Journal of the Royal Medical Services. 2022. Vol. 29, no. 1, pp.22-27.
https://search.emarefa.net/detail/BIM-1435374
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 26-27
رقم السجل
BIM-1435374
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر