A meta-analysis of the effects and safety of pulmonary surfactants : combined with budesonide in bronchopulmonary dysplasia
المؤلفون المشاركون
He, Bing Bin
Liu, Guo Sheng
Zhuang, Jia Yong
Ye, Bo Ran
المصدر
Iranian Red Crescent Medical Journal
العدد
المجلد 22، العدد 6 (30 يونيو/حزيران 2020)، ص ص. 1-9، 9ص.
الناشر
تاريخ النشر
2020-06-30
دولة النشر
الإمارات العربية المتحدة
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Context: The purpose of this analysis was to explore the effects and safety of Pulmonary Surfactants (PS) combined with budesonide in Bronchopulmonary Dysplasia (BPD) by a meta-analysis of Randomized Controlled Trials (RCTs).
Evidence acquisition: Literature searches were performed in PubMed, the Cochrane Library, EMBASE, the China Knowledge Net- work, and the Wanfang database to collect data from RCTs.
The primary outcomes were BPD incidence and BPD-related mortal- ity, while the secondary outcomes were BPD-related complications.
Bias was evaluated by the Cochrane risk assessment tool.
The RevMan 5.3 software was used for the meta-analysis, and the Egger’s test was used for publication bias assessment.
Results: A total of 720 subjects were enrolled from six RCTs, including 352 in the experimental group and 368 in the observation group.
The BPD incidence (RR = 0.
42, 95% CI [0.
37, 0.
89], P < 0.001) and BPD-related mortality (RR = 0.54, 95% CI [0.38, 0.89], P < 0.05) differed significantly between the two groups.
Significant differences were also found in intraventricular hemorrhage, infection/sepsis, Retinopathy of Prematurity (ROP), and Patent Ductus Arteriosus (PDA).
There were no significant differences in the incidence of PDA, Neonatal Necrotizing Enterocolitis (NEC), hyperglycemia, and hypertension.
Conclusions: The intratracheal instillation of pulmonary surfactants with budesonide can reduce the incidence of BPD and BPD- related mortality with no increased risk of short-term complications.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
He, Bing Bin& Liu, Guo Sheng& Zhuang, Jia Yong& Ye, Bo Ran. 2020. A meta-analysis of the effects and safety of pulmonary surfactants : combined with budesonide in bronchopulmonary dysplasia. Iranian Red Crescent Medical Journal،Vol. 22, no. 6, pp.1-9.
https://search.emarefa.net/detail/BIM-1437567
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
He, Bing Bin…[et al.]. A meta-analysis of the effects and safety of pulmonary surfactants : combined with budesonide in bronchopulmonary dysplasia. Iranian Red Crescent Medical Journal Vol. 22, no. 6 (Jun. 2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1437567
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
He, Bing Bin& Liu, Guo Sheng& Zhuang, Jia Yong& Ye, Bo Ran. A meta-analysis of the effects and safety of pulmonary surfactants : combined with budesonide in bronchopulmonary dysplasia. Iranian Red Crescent Medical Journal. 2020. Vol. 22, no. 6, pp.1-9.
https://search.emarefa.net/detail/BIM-1437567
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 8-9
رقم السجل
BIM-1437567
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر