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A meta-analysis of the effects and safety of pulmonary surfactants : combined with budesonide in bronchopulmonary dysplasia
المؤلفون المشاركون
He, Bing Bin
Liu, Guo Sheng
Zhuang, Jia Yong
Ye, Bo Ran
المصدر
Iranian Red Crescent Medical Journal
العدد
المجلد 22، العدد 6 (30 يونيو/حزيران 2020)، ص ص. 1-9، 9ص.
الناشر
تاريخ النشر
2020-06-30
دولة النشر
الإمارات العربية المتحدة
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Context: The purpose of this analysis was to explore the effects and safety of Pulmonary Surfactants (PS) combined with budesonide in Bronchopulmonary Dysplasia (BPD) by a meta-analysis of Randomized Controlled Trials (RCTs).
Evidence acquisition: Literature searches were performed in PubMed, the Cochrane Library, EMBASE, the China Knowledge Net- work, and the Wanfang database to collect data from RCTs.
The primary outcomes were BPD incidence and BPD-related mortal- ity, while the secondary outcomes were BPD-related complications.
Bias was evaluated by the Cochrane risk assessment tool.
The RevMan 5.3 software was used for the meta-analysis, and the Egger’s test was used for publication bias assessment.
Results: A total of 720 subjects were enrolled from six RCTs, including 352 in the experimental group and 368 in the observation group.
The BPD incidence (RR = 0.
42, 95% CI [0.
37, 0.
89], P < 0.001) and BPD-related mortality (RR = 0.54, 95% CI [0.38, 0.89], P < 0.05) differed significantly between the two groups.
Significant differences were also found in intraventricular hemorrhage, infection/sepsis, Retinopathy of Prematurity (ROP), and Patent Ductus Arteriosus (PDA).
There were no significant differences in the incidence of PDA, Neonatal Necrotizing Enterocolitis (NEC), hyperglycemia, and hypertension.
Conclusions: The intratracheal instillation of pulmonary surfactants with budesonide can reduce the incidence of BPD and BPD- related mortality with no increased risk of short-term complications.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
He, Bing Bin& Liu, Guo Sheng& Zhuang, Jia Yong& Ye, Bo Ran. 2020. A meta-analysis of the effects and safety of pulmonary surfactants : combined with budesonide in bronchopulmonary dysplasia. Iranian Red Crescent Medical Journal،Vol. 22, no. 6, pp.1-9.
https://search.emarefa.net/detail/BIM-1437567
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
He, Bing Bin…[et al.]. A meta-analysis of the effects and safety of pulmonary surfactants : combined with budesonide in bronchopulmonary dysplasia. Iranian Red Crescent Medical Journal Vol. 22, no. 6 (Jun. 2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1437567
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
He, Bing Bin& Liu, Guo Sheng& Zhuang, Jia Yong& Ye, Bo Ran. A meta-analysis of the effects and safety of pulmonary surfactants : combined with budesonide in bronchopulmonary dysplasia. Iranian Red Crescent Medical Journal. 2020. Vol. 22, no. 6, pp.1-9.
https://search.emarefa.net/detail/BIM-1437567
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 8-9
رقم السجل
BIM-1437567
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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