Determination of normal and variant hemoglobin using capillary electrophoresis among voluntary blood donors in north central Nigeria : implications on blood transfusion services
المؤلفون المشاركون
Durotoye, Idayat Adenike
Salaudeen, Adekunle Ganiyu
Sanni, Emmanuel Oladipo
Babatunde, Abiola Samuel
Durowade, Adekunle Kabir
Olawumi, Hannah Oluwayemisi
Akande, Tanimola Makanjuola
Musa, Omotosho Ibrahim
المصدر
Sudan Journal of Medical Sciences
العدد
المجلد 16، العدد 1 (31 مارس/آذار 2021)، ص ص. 33-42، 10ص.
الناشر
جامعة أم درمان الإسلامية كلية الطب
تاريخ النشر
2021-03-31
دولة النشر
السودان
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Background: Voluntary non-remunerated blood donation is a strategy adopted by World Health Organization aimed at ensuring safety and adequacy of blood supply.
Sub-Saharan Africa has a high prevalence of hemoglobin disorders and therefore needs to adopt stringent measures in donor selection to ensure safety for the recipient of blood transfusion.
This study aimed to analyze normal and variant hemoglobin among voluntary blood donors.
Methods: In this descriptive cross-sectional study, 100 prospective blood donors including 55 (55%) males and 45 (45%) females, aged 18–34 years were recruited.
Capillary electrophoresis using the Minicap system was used for determining the hemoglobin variants in alkaline buffer (PH 9.4).
Data analysis was done using SPSS version 20 and p-value < 0.05 was considered as the level of significance Results: The mean age of the participants was 22.23 ± 3.3 SD years.
The proportion of participants with genotype AA was 67 (67%), those with AS were 17 (22 %), while those with AC were 11 (11 %).
While Hb A ≥ 90% was noted in 67 (67%) blood donors, Hb S was seen in 22 (22%) and Hb A2 > 3.5% in 57 (57%).
Hb F > 2% was observed in 3% of the studied participants Conclusion: Variant hemoglobin is common among blood donors and this should be taken into consideration whenever blood is being crossmatched for recipients of blood transfusion.
Data from this study will be useful in raising awareness and genetic counseling.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Durotoye, Idayat Adenike& Salaudeen, Adekunle Ganiyu& Sanni, Emmanuel Oladipo& Babatunde, Abiola Samuel& Durowade, Adekunle Kabir& Olawumi, Hannah Oluwayemisi…[et al.]. 2021. Determination of normal and variant hemoglobin using capillary electrophoresis among voluntary blood donors in north central Nigeria : implications on blood transfusion services. Sudan Journal of Medical Sciences،Vol. 16, no. 1, pp.33-42.
https://search.emarefa.net/detail/BIM-1439602
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Durotoye, Idayat Adenike…[et al.]. Determination of normal and variant hemoglobin using capillary electrophoresis among voluntary blood donors in north central Nigeria : implications on blood transfusion services. Sudan Journal of Medical Sciences Vol. 16, no. 1 (2021), pp.33-42.
https://search.emarefa.net/detail/BIM-1439602
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Durotoye, Idayat Adenike& Salaudeen, Adekunle Ganiyu& Sanni, Emmanuel Oladipo& Babatunde, Abiola Samuel& Durowade, Adekunle Kabir& Olawumi, Hannah Oluwayemisi…[et al.]. Determination of normal and variant hemoglobin using capillary electrophoresis among voluntary blood donors in north central Nigeria : implications on blood transfusion services. Sudan Journal of Medical Sciences. 2021. Vol. 16, no. 1, pp.33-42.
https://search.emarefa.net/detail/BIM-1439602
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 40-42
رقم السجل
BIM-1439602
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر