Unexpected diagnosis of complete androgen insensitivity syndrome (CAIS) during inguinal hernia repair in 11-year-old-girl
المؤلفون المشاركون
Khalid, Rayyan
Sadiq, Ala M.
Abuduam, Abd al-Rahman A.
al-Zayn, Abd al-Baqi
al-Mulla, Imad Fadl
المصدر
Sudan Journal of Medical Sciences
العدد
المجلد 16، العدد 1 (31 مارس/آذار 2021)، ص ص. 70-75، 6ص.
الناشر
جامعة أم درمان الإسلامية كلية الطب
تاريخ النشر
2021-03-31
دولة النشر
السودان
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Complete Androgen Insensitivity Syndrome (CAIS) is an X-link recessive genetic mutation of androgen receptor (AR) gene leading to complete inability of cell to respond to the androgens.
CAIS occurs in 1 out of 20,400 XY live-birth babies, and affects about 1–2% of prepubertal girls that present with an inguinal hernia.
Although individuals with CAIS have XY, those with grades 6 and 7 on the Quigley scale are born phenotypically female, without any signs of genital masculinization.
Thus, individuals affected by CAIS develop a normal external female phenotype with normal female external genitalia, well-developed breast, absent uterus, and bilateral undescended testicles.
The question of CAIS diagnosis does not come forward until the absent menses at the puberty is noted or accidentally during an inguinal hernia repair in a premenarchal girl.
The present study reports a case of inguinal hernia repair on 11- year-old girl, which led to unexpected intraoperative notion of CAIS.
The diagnostic work-up, genetic counseling, sex assignment, and the need for preoperative CAIS screening in girls with bilateral inguinal hernia are described and discussed.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Khalid, Rayyan& Sadiq, Ala M.& Abuduam, Abd al-Rahman A.& al-Zayn, Abd al-Baqi& al-Mulla, Imad Fadl. 2021. Unexpected diagnosis of complete androgen insensitivity syndrome (CAIS) during inguinal hernia repair in 11-year-old-girl. Sudan Journal of Medical Sciences،Vol. 16, no. 1, pp.70-75.
https://search.emarefa.net/detail/BIM-1439614
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Khalid, Rayyan…[et al.]. Unexpected diagnosis of complete androgen insensitivity syndrome (CAIS) during inguinal hernia repair in 11-year-old-girl. Sudan Journal of Medical Sciences Vol. 16, no. 1 (2021), pp.70-75.
https://search.emarefa.net/detail/BIM-1439614
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Khalid, Rayyan& Sadiq, Ala M.& Abuduam, Abd al-Rahman A.& al-Zayn, Abd al-Baqi& al-Mulla, Imad Fadl. Unexpected diagnosis of complete androgen insensitivity syndrome (CAIS) during inguinal hernia repair in 11-year-old-girl. Sudan Journal of Medical Sciences. 2021. Vol. 16, no. 1, pp.70-75.
https://search.emarefa.net/detail/BIM-1439614
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 74-75
رقم السجل
BIM-1439614
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر