Magnetic resonance imaging-negative myeloneuropathy and bilateral facial paresis unfurling systemic lupus erythematosus

المؤلفون المشاركون

Ghosh, Ritwik
Das, Shambaditya
Dubey, Souvik
Benito Leon, Julian
De, Koustav

المصدر

Qatar Medical Journal

العدد

المجلد 2022، العدد 3 (31 ديسمبر/كانون الأول 2022)، ص ص. 1-7، 7ص.

الناشر

مؤسسة حمد الطبية

تاريخ النشر

2022-12-31

دولة النشر

قطر

عدد الصفحات

7

التخصصات الرئيسية

الطب البشري

الملخص EN

Systemic lupus erythematosus is a chronic autoimmune connective tissue disorder that can affect all the neuroaxes in the central and peripheral nervous systems.

Myelopathy in systemic lupus erythematosus is one of the least common neuropsychiatric syndromes accounting for 1%–2% of cases.

Myelopathy has long been diagnosed based on clinical findings, laboratory tests, and gold-standard gadolinium-enhanced magnetic resonance imaging (MRI).

MRI-negative myelopathy is a recently described subset of myelopathies.

Here, we report the case of a young woman from rural West Bengal, India, who presented with overlapping features of white-matter and gray-matter myelopathy associated with peripheral neuropathy and bilateral asymmetric lower motor neuron-type facial paresis.

The historical analysis yielded clues toward an etiological diagnosis of systemic lupus erythematosus, further substantiated by seropositivity of lupus-specific autoantibodies.

Her neurological disabilities responded poorly to oral administration of hydroxychloroquine, bolus intravenous administration of methylprednisolone, and high-dose cyclophosphamide therapy but eventually responded remarkably well to cyclical rituximab therapy.

This case adds to the tally of cases of MRI-negative lupus myelopathy.

MRI-negative myelopathy in systemic lupus erythematosus can be easily missed if not meticulous attention is paid during clinical history taking and examinations.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Ghosh, Ritwik& Das, Shambaditya& De, Koustav& Dubey, Souvik& Benito Leon, Julian. 2022. Magnetic resonance imaging-negative myeloneuropathy and bilateral facial paresis unfurling systemic lupus erythematosus. Qatar Medical Journal،Vol. 2022, no. 3, pp.1-7.
https://search.emarefa.net/detail/BIM-1439722

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Ghosh, Ritwik…[et al.]. Magnetic resonance imaging-negative myeloneuropathy and bilateral facial paresis unfurling systemic lupus erythematosus. Qatar Medical Journal No. 3 (2022), pp.1-7.
https://search.emarefa.net/detail/BIM-1439722

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Ghosh, Ritwik& Das, Shambaditya& De, Koustav& Dubey, Souvik& Benito Leon, Julian. Magnetic resonance imaging-negative myeloneuropathy and bilateral facial paresis unfurling systemic lupus erythematosus. Qatar Medical Journal. 2022. Vol. 2022, no. 3, pp.1-7.
https://search.emarefa.net/detail/BIM-1439722

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references : p. 6-7

رقم السجل

BIM-1439722