Sarcoidosis of the pineal region, dorsal mesencephalon, and periaqueductal region : case report and systematic review
المؤلفون المشاركون
Bin Nabi, Walid
Aichaui, Faysal
Mziani, Salim
Mursuli, Abd al-Halimi
Khalifah, Adil Muhammad
المصدر
العدد
المجلد 2021، العدد 2 (31 أغسطس/آب 2021)، ص ص. 1-9، 9ص.
الناشر
تاريخ النشر
2021-08-31
دولة النشر
قطر
عدد الصفحات
9
التخصصات الرئيسية
العلوم الطبية والصيدلة والعلوم الصحية
الملخص EN
Background: The central nervous system is an unusual location of sarcoidosis, which commonly affects the cranial nerves, meninges, hypothalamus, and pituitary gland.
Involvement of the pineal region is extremely rare.
This systematic review focused on the diagnosis and management of pineal region sarcoidosis, dorsal mesencephalon, and periaqueductal region.
Objectives: This study aimed to discuss diagnostic modalities and best management tools of the aforementioned pathology.
Methods: ScienceDirect, PubMed, and Google Scholar databases were searched for English or French articles about sarcoidosis of the pineal region, dorsal mesencephalon, and periaqueductal region.
The clinical case of a patient managed at our department that we believe is directly relevant to this review is also presented.
Patients' demographics, clinical pre- sentations, presence of hydrocephalus, other sarcoi- dosis locations in the central nervous system, and medical treatment were collected.
Surgical manage- ment, surgical approach, and outcomes and compli- cations of each procedure were also obtained.
This study was conducted in agreement with the Preferred Reporting Items for Systematic Reviews and Meta- Analyses statement.
Results: Fifteen cases were examined.
The study sample consisted of nine (60%) male and six (40%) female, and the mean age was 32 years.
Eight (53%) patients had hydrocephalus, and the predominant clinical presentations were signs of increasing intracranial pressure (headaches, vomiting, and papilledema).
Six (40%) patients had diplopia, and convergence–retraction nystagmus was noted in three (20%) patients.
Argyll Robertson sign was present in one patient and suspected in another patient (13%).
Medical treatment consisted mainly of steroids (93% of cases).
Open surgery on the pineal region was performed in five patients, and four of them reported to have serious complications (such as ophthalmoplegia, hemianopsia, hemiparesis, bilateral third cranial nerve paresis, and cerebellar syndrome).
Endoscopic management was performed in two patients without complications.
Conclusion: To treat hydrocephalus, brain imaging is mandatory in patients with sarcoidosis if intracranial hypertension is suspected.
In pineal region sarcoidosis, management of hydrocephalus is the priority, followed by medical treatment of the lesion.
Open surgery of any approach presents a high risk of complications; thus, an endoscopic approach is the preferred management, as it treats hydrocephalus and makes biopsy possible with minimal risk.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Khalifah, Adil Muhammad& Bin Nabi, Walid& Aichaui, Faysal& Mziani, Salim& Mursuli, Abd al-Halimi. 2021. Sarcoidosis of the pineal region, dorsal mesencephalon, and periaqueductal region : case report and systematic review. Qatar Medical Journal،Vol. 2021, no. 2, pp.1-9.
https://search.emarefa.net/detail/BIM-1442086
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Khalifah, Adil Muhammad…[et al.]. Sarcoidosis of the pineal region, dorsal mesencephalon, and periaqueductal region : case report and systematic review. Qatar Medical Journal No. 2 (2021), pp.1-9.
https://search.emarefa.net/detail/BIM-1442086
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Khalifah, Adil Muhammad& Bin Nabi, Walid& Aichaui, Faysal& Mziani, Salim& Mursuli, Abd al-Halimi. Sarcoidosis of the pineal region, dorsal mesencephalon, and periaqueductal region : case report and systematic review. Qatar Medical Journal. 2021. Vol. 2021, no. 2, pp.1-9.
https://search.emarefa.net/detail/BIM-1442086
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 8-9
رقم السجل
BIM-1442086
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر