The potential effects of cerium oxide nanoparticles against ferrous sulfate-induced oxidative stress in male albino rats
المؤلفون المشاركون
Abbas, Manal Munir
Mahmud, Amal H.
Abd al-Munim, Hanan A.
المصدر
Arab Journal of Nuclear Sciences and Applications
العدد
المجلد 56، العدد 1 (31 يناير/كانون الثاني 2023)، ص ص. 41-48، 8ص.
الناشر
الجمعية المصرية للعلوم النووية و تطبيقاتها
تاريخ النشر
2023-01-31
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الموضوعات
الملخص EN
Iron is a vitally essential element for the maintenance of health in the living organism however ; iron overload can have harmful effects on health.
nanoparticles constitute a therapeutic approach for the remedy of many disorders.
so the study was performed to examine the potential ameliorative effects of cerium oxide nanoparticles (CeONPs) against ferrous sulfate (FS) induced oxidative stress, hepatic, renal and thyroid functional disorders in rats.
twenty-eight male albino rats were equally assigned into four groups.
Group 1 received 1 ml saline (control), FS group rats received ferrous sulfate (30 mg / Kg / day), CeONPs group (0.5 mg / Kg / day) and the fourth group received CeONPs + FS (0.5 mg / Kg + 30 mg / Kg).
rats in all groups were injected intraperitoneally for two weeks (5 days / week).
results revealed that FS increased serum levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), total bilirubin, total protein, creatinine, and urea.
in addition, hepatic and renal levels of malondialdehyde (MDA) were increased while glutathione (GSH), superoxide dismutase (SOD) levels in the liver, kidney and serum thyroxine level were reduced.
treatment with CeONPs restored liver, kidney and thyroid functions to almost the normal levels and improved the oxidant-antioxidant status.
so the study pointed to the ameliorative effect of CeONPs against Fs-induced disorders on oxidative stress, liver, kidney and thyroid function.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Mahmud, Amal H.& Abbas, Manal Munir& Abd al-Munim, Hanan A.. 2023. The potential effects of cerium oxide nanoparticles against ferrous sulfate-induced oxidative stress in male albino rats. Arab Journal of Nuclear Sciences and Applications،Vol. 56, no. 1, pp.41-48.
https://search.emarefa.net/detail/BIM-1443598
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Mahmud, Amal H.…[et al.]. The potential effects of cerium oxide nanoparticles against ferrous sulfate-induced oxidative stress in male albino rats. Arab Journal of Nuclear Sciences and Applications Vol. 56, no. 1 (Jan. 2023), pp.41-48.
https://search.emarefa.net/detail/BIM-1443598
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Mahmud, Amal H.& Abbas, Manal Munir& Abd al-Munim, Hanan A.. The potential effects of cerium oxide nanoparticles against ferrous sulfate-induced oxidative stress in male albino rats. Arab Journal of Nuclear Sciences and Applications. 2023. Vol. 56, no. 1, pp.41-48.
https://search.emarefa.net/detail/BIM-1443598
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 46-48
رقم السجل
BIM-1443598
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر