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Validation of SARS-CoV-2 serological essay, Bahrain experience
المؤلفون المشاركون
al- Sayyad, Adil S.
Muhammad, Amjad G.
Shihab, Fatimah E.
Muhammad, Kubra N.
al-Qassab, Narjis Y.
Abu al-Fath, Najah M.
al-Hajiri, Maryam E.
Muhammad, Afaf M.
المصدر
العدد
المجلد 42، العدد 4 (31 ديسمبر/كانون الأول 2020)، ص ص. 240-243، 4ص.
الناشر
تاريخ النشر
2020-12-31
دولة النشر
البحرين
عدد الصفحات
4
التخصصات الرئيسية
العلوم الطبية والصيدلة والعلوم الصحية
الملخص EN
Background: The standard test for diagnosing Coronavirus disease (COVID-19) is the polymerase chain reaction (PCR) test.
Since the start of the pandemic, there has been a rush in the development of tests that can detect the presence of antibodies produced by COVID-19 cases as a response to the exposure to the SARS-CoV-2 virus.
Objective: To evaluate the validity of the serology tests for detecting SARS-CoV-2 protective IgG antibodies.
Design: Cross-Sectional Prospective Study.
Setting: COVID-19 Testing and Caring Facilities, Kingdom of Bahrain.
Method: From 22 June to 1 July 2020, healthcare workers, non-national laborers, symptomatic and asymptomatic patients were included in the study.
All patients underwent PCR and serology tests.
The presence of IgG antibodies among participants were measured.
The sensitivity and specificity of the serology tests were evaluated.
Result: Three hundred eighty-eight participants were included in the study; the mean age was 40±13 years.
Two-hundred thirty-two (59.7%) were males and 242 (62.3%) were Bahrainis.
Seventy-three (18.8%) were healthcare workers, 87 (22.4%) were non-national laborers, 109 (28.1%) were symptomatic and 119 (30.7%) were asymptomatic.
One hundred sixty-four (42.2%) participants were COVID-19 positive.
Ninety-six (24.7%) had a positive serology test with IgG level >1.4.
The sensitivity of the serology test at 14 days was 84.4% (CI: 67.2%-94.7%).
The specificity of the test was 93.3% (CI: 89.2%-96.2%).
Conclusion: The sensitivity of the serology test to detect the IgG antibodies 14 days after testing positive with COVID-19 was 84% and the specificity was 93.3%.
The result supports the use of the test in a serosurvey study.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Muhammad, Afaf M.& al- Sayyad, Adil S.& Muhammad, Amjad G.& Shihab, Fatimah E.& Abu al-Fath, Najah M.& al-Hajiri, Maryam E.…[et al.]. 2020. Validation of SARS-CoV-2 serological essay, Bahrain experience. Bahrain Medical Bulletin،Vol. 42, no. 4, pp.240-243.
https://search.emarefa.net/detail/BIM-1451641
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Abu al-Fath, Najah M.…[et al.]. Validation of SARS-CoV-2 serological essay, Bahrain experience. Bahrain Medical Bulletin Vol. 42, no. 4 (Dec. 2020), pp.240-243.
https://search.emarefa.net/detail/BIM-1451641
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Muhammad, Afaf M.& al- Sayyad, Adil S.& Muhammad, Amjad G.& Shihab, Fatimah E.& Abu al-Fath, Najah M.& al-Hajiri, Maryam E.…[et al.]. Validation of SARS-CoV-2 serological essay, Bahrain experience. Bahrain Medical Bulletin. 2020. Vol. 42, no. 4, pp.240-243.
https://search.emarefa.net/detail/BIM-1451641
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
رقم السجل
BIM-1451641
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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