Diseases associated with the different patterns of antinuclear antibodies detected by immunofluorescence
العناوين الأخرى
أمراض المصاحبة للأنماط المختلفة من أضداد النوى المتحراة بالومضان المناعي
المصدر
Journal of the Arab Board of Health Specializations
العدد
المجلد 5، العدد 3 (31 أغسطس/آب 2003)، ص ص. 18-23، 6ص.
الناشر
المجلس العربي للاختصاصات الصحية
تاريخ النشر
2003-08-31
دولة النشر
سوريا
عدد الصفحات
6
التخصصات الرئيسية
الملخص AR
Backgrounds: Immunofluorescent antinuclear antibody (ANA) patterns are variable and may indicate specificity towards certain diagnoses.
Objectives: To explore the spectrum of diseases associated with the common different ANA patterns seen at King Abdulaziz University Hospital (KAUH).
Methods: ANA tests were performed by indirect immunofluorescent assay (UFA) in the clinical immunology laboratory.
Cases with positive ANA were selected sequentially.
Their UFA patterns and patient files were reviewed.
Resulls: 211 positive ANA cases were studied.
The ages ranged between 3- females predominated (83%).
Rheumatological disorders were the predominant illnesses; they were diagnosed in 148 cases (70.1%).
These included systemic lupus erythematosus (SLE) 71 (33.6%), rheumatoid arthritis 18 (8.5%), others 26 (12.3%), and undiagnosed 33 (15.6%).
Other autoimmune disorders followed with 34 (16.1%).
There were also 23 (10.9%) cases with recurrent abortion and 6 (2.8%)with miscellaneous illnesses.
The different ANA patterns on UFA were: homogeneous 107 (50.7%), speckled 68 (32.2%), nuclear 18 (8.5%), peripheral 7 (3.3%), centromere 1 (0.5%), and mixed 10 (4.7%).
A highly significant association was detected between the peripheral ANA pattern and SLE cases (P<0.01).
Conclusion: Autoimmune disorders, particularly rheumatological, were the commonest diseases associated with positive ANA test.
The predominant ANA pattern was the homogeneous, followed by the speckled which is compatible with reports in the literarture.
ANA staining pattern have limited value in the clinical assessment of autoimmune diseases; however, ANA has very high sensitivity for SLE especially in cases with peripheral ANA pattern.
الملخص EN
Backgrounds: Immunofluorescent antinuclear antibody (ANA) patterns are variable and may indicate specificity towards certain diagnoses.
Objectives: To explore the spectrum of diseases associated with the common different ANA patterns seen at King Abdulaziz University Hospital (KAUH).
Methods: ANA tests were performed by indirect immunofluorescent assay (UFA) in the clinical immunology laboratory.
Cases with positive ANA were selected sequentially.
Their UFA patterns and patient files were reviewed.
Resulls: 211 positive ANA cases were studied.
The ages ranged between 3- females predominated (83%).
Rheumatological disorders were the predominant illnesses; they were diagnosed in 148 cases (70.1%).
These included systemic lupus erythematosus (SLE) 71 (33.6%), rheumatoid arthritis 18 (8.5%), others 26 (12.3%), and undiagnosed 33 (15.6%).
Other autoimmune disorders followed with 34 (16.1%).
There were also 23 (10.9%) cases with recurrent abortion and 6 (2.8%)with miscellaneous illnesses.
The different ANA patterns on UFA were: homogeneous 107 (50.7%), speckled 68 (32.2%), nuclear 18 (8.5%), peripheral 7 (3.3%), centromere 1 (0.5%), and mixed 10 (4.7%).
A highly significant association was detected between the peripheral ANA pattern and SLE cases (P<0.01).
Conclusion: Autoimmune disorders, particularly rheumatological, were the commonest diseases associated with positive ANA test.
The predominant ANA pattern was the homogeneous, followed by the speckled which is compatible with reports in the literarture.
ANA staining pattern have limited value in the clinical assessment of autoimmune diseases; however, ANA has very high sensitivity for SLE especially in cases with peripheral ANA pattern.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Koshak, Imad A.. 2003. Diseases associated with the different patterns of antinuclear antibodies detected by immunofluorescence. Journal of the Arab Board of Health Specializations،Vol. 5, no. 3, pp.18-23.
https://search.emarefa.net/detail/BIM-146400
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Koshak, Imad A.. Diseases associated with the different patterns of antinuclear antibodies detected by immunofluorescence. Journal of the Arab Board of Health Specializations Vol. 5, no. 3(August 2003), pp.18-23.
https://search.emarefa.net/detail/BIM-146400
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Koshak, Imad A.. Diseases associated with the different patterns of antinuclear antibodies detected by immunofluorescence. Journal of the Arab Board of Health Specializations. 2003. Vol. 5, no. 3, pp.18-23.
https://search.emarefa.net/detail/BIM-146400
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 22-23
رقم السجل
BIM-146400
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر