Primary langerhans cell histiocytosis of the small bowel : report of three cases
العناوين الأخرى
أدوات خلايا لانغرهانس الناسجة البدئية في الأمعاء الدقيقة : تقرير لثلاث حالات
المصدر
Journal of the Arab Board of Health Specializations
العدد
المجلد 5، العدد 1 (28 فبراير/شباط 2003)، ص ص. 25-31، 7ص.
الناشر
المجلس العربي للاختصاصات الصحية
تاريخ النشر
2003-02-28
دولة النشر
سوريا
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background: Langerhans cell histiocytosis (LCH) represents a spectrum of disorders involving several tissues and organs which is characterized by proliferation of Langerhans histiocytes and various inflammatory cells.
The gastrointestinal tract may be involved in LCH, either as part of a generalized disease or as a separate primary entity.
Methods: Three cases of LCH with primary small bowel involvement were reviewed in the Department of Pathology at Al Assad University Hospital in Latakia in the period from l993-l999.
The identity of Langerhans cells was confirmed by immunohistochemical stains.
The patients were 2 men and l woman, aged 29, 44, and 68 years, each of whom presented with a history of chronic gastroenteritis and malabsorption syndrome.
One patient had an acute abdominal crisis associated with intestinal perforation.
Laparotomy was performed which revealed severe inflammation of the distal duodenum, the jejenum, and the proximal part of the ileum as well as many enlarged and congested mesenteric lymph nodes.
Results: Biopsy specimen obtained by endoscopy or from surgical resection of the small bowel (3rd case) revealed variable degrees of villous atrophy, dense inflammatory cell infiltrate of the lamina propria and submucosa by histiocytes, lymphocytes and a few eosinophils.
Some of the histiocytes showed the characteristic folded and grooved nuclei that identified them as Langerhans cells.
The majority of Langerhans cells expressed positive immunostains for CDla and Sl00.
Conclusion : This study included three cases of LCH involving the small bowel without systemic dissemination.
Because of the absence of recognized systemic manifestations, the histologic diagnosis was delaye.
Awareness of the unusual clinical presentation of LCH involving the small bowel may facilitate earlier accurate histologic diagnosis of this entity.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Shihabi, Zuhayr& Zayzafoun, Hassan. 2003. Primary langerhans cell histiocytosis of the small bowel : report of three cases. Journal of the Arab Board of Health Specializations،Vol. 5, no. 1, pp.25-31.
https://search.emarefa.net/detail/BIM-147420
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Shihabi, Zuhayr& Zayzafoun, Hassan. Primary langerhans cell histiocytosis of the small bowel : report of three cases. Journal of the Arab Board of Health Specializations Vol. 5, no. 1 (Feb. 2003), pp.25-31.
https://search.emarefa.net/detail/BIM-147420
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Shihabi, Zuhayr& Zayzafoun, Hassan. Primary langerhans cell histiocytosis of the small bowel : report of three cases. Journal of the Arab Board of Health Specializations. 2003. Vol. 5, no. 1, pp.25-31.
https://search.emarefa.net/detail/BIM-147420
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 30-31
رقم السجل
BIM-147420
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر