Association between inflammatory cytokines and liver functions in rheumatoid arthritis patients
المؤلفون المشاركون
Ismail, Ammar Muhammad
al-Tahir, Muhammad Abd al-Rahman
Salih, Kawthar Abd al-Jalil Muhammad
Muhammad, al-Hajj Nur al-Din
Babakir, Faysal Makki
المصدر
Sudan Journal of Medical Sciences
العدد
المجلد 16، العدد 2 (30 يونيو/حزيران 2021)، ص ص. 276-284، 9ص.
الناشر
جامعة أم درمان الإسلامية كلية الطب
تاريخ النشر
2021-06-30
دولة النشر
السودان
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Background : rheumatoid arthritis (RA) is associated with abnormal liver tests, and the medications used for RA are often hepatotoxic.
therefore, this study aimed to investigate an association between pro-inflammatory and anti-inflammatory cytokines and liver function tests in RA patients.
methods : in this descriptive cross-sectional study, 88 RA patients were included, 84 of them were women and 4 men, aged 21–81 years.
Serum interleukin-10 (IL-10), interleukin-17 (IL-17), Osteopontin (OPN) were measured and liver function tests were conducted.
results : the frequency of RA was higher among adults aged >41 years (72 [81.8%]) than young adults aged ≤41 years (16 [18.2%]).
RA was more common in women (84 [95.5%]) than in men (4 [4.5%]) – approximately 21:1-fold.
Young adults had higher abnormal IL-10 than adult RA patients (OR = 3.72, p-value 0.044).
abnormal IL-17 (OR = 5.67, p-value 0.034) was found to be increased in young-adult RA patients.
No association was observed between age and OPN and between the duration of disease and IL-10, IL-17, and OPN.
similarly, no association was noted between the types of treatment and IL-10, IL-17, and OPN, nor between IL-10, IL-17, OPN and liver parameters (AST, ALT, ALP, ALB, TP, and GGT).
conclusion : pro-inflammatory and anti-inflammatory cytokines are not associated with abnormal liver functions, as has been demonstrated in RA patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Tahir, Muhammad Abd al-Rahman& Salih, Kawthar Abd al-Jalil Muhammad& Muhammad, al-Hajj Nur al-Din& Babakir, Faysal Makki& Ismail, Ammar Muhammad. 2021. Association between inflammatory cytokines and liver functions in rheumatoid arthritis patients. Sudan Journal of Medical Sciences،Vol. 16, no. 2, pp.276-284.
https://search.emarefa.net/detail/BIM-1491578
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Tahir, Muhammad Abd al-Rahman…[et al.]. Association between inflammatory cytokines and liver functions in rheumatoid arthritis patients. Sudan Journal of Medical Sciences Vol. 16, no. 2 (2021), pp.276-284.
https://search.emarefa.net/detail/BIM-1491578
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Tahir, Muhammad Abd al-Rahman& Salih, Kawthar Abd al-Jalil Muhammad& Muhammad, al-Hajj Nur al-Din& Babakir, Faysal Makki& Ismail, Ammar Muhammad. Association between inflammatory cytokines and liver functions in rheumatoid arthritis patients. Sudan Journal of Medical Sciences. 2021. Vol. 16, no. 2, pp.276-284.
https://search.emarefa.net/detail/BIM-1491578
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 282-284
رقم السجل
BIM-1491578
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر