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Association between inflammatory cytokines and liver functions in rheumatoid arthritis patients
المؤلفون المشاركون
Ismail, Ammar Muhammad
al-Tahir, Muhammad Abd al-Rahman
Salih, Kawthar Abd al-Jalil Muhammad
Muhammad, al-Hajj Nur al-Din
Babakir, Faysal Makki
المصدر
Sudan Journal of Medical Sciences
العدد
المجلد 16، العدد 2 (30 يونيو/حزيران 2021)، ص ص. 276-284، 9ص.
الناشر
جامعة أم درمان الإسلامية كلية الطب
تاريخ النشر
2021-06-30
دولة النشر
السودان
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Background : rheumatoid arthritis (RA) is associated with abnormal liver tests, and the medications used for RA are often hepatotoxic.
therefore, this study aimed to investigate an association between pro-inflammatory and anti-inflammatory cytokines and liver function tests in RA patients.
methods : in this descriptive cross-sectional study, 88 RA patients were included, 84 of them were women and 4 men, aged 21–81 years.
Serum interleukin-10 (IL-10), interleukin-17 (IL-17), Osteopontin (OPN) were measured and liver function tests were conducted.
results : the frequency of RA was higher among adults aged >41 years (72 [81.8%]) than young adults aged ≤41 years (16 [18.2%]).
RA was more common in women (84 [95.5%]) than in men (4 [4.5%]) – approximately 21:1-fold.
Young adults had higher abnormal IL-10 than adult RA patients (OR = 3.72, p-value 0.044).
abnormal IL-17 (OR = 5.67, p-value 0.034) was found to be increased in young-adult RA patients.
No association was observed between age and OPN and between the duration of disease and IL-10, IL-17, and OPN.
similarly, no association was noted between the types of treatment and IL-10, IL-17, and OPN, nor between IL-10, IL-17, OPN and liver parameters (AST, ALT, ALP, ALB, TP, and GGT).
conclusion : pro-inflammatory and anti-inflammatory cytokines are not associated with abnormal liver functions, as has been demonstrated in RA patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Tahir, Muhammad Abd al-Rahman& Salih, Kawthar Abd al-Jalil Muhammad& Muhammad, al-Hajj Nur al-Din& Babakir, Faysal Makki& Ismail, Ammar Muhammad. 2021. Association between inflammatory cytokines and liver functions in rheumatoid arthritis patients. Sudan Journal of Medical Sciences،Vol. 16, no. 2, pp.276-284.
https://search.emarefa.net/detail/BIM-1491578
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Tahir, Muhammad Abd al-Rahman…[et al.]. Association between inflammatory cytokines and liver functions in rheumatoid arthritis patients. Sudan Journal of Medical Sciences Vol. 16, no. 2 (2021), pp.276-284.
https://search.emarefa.net/detail/BIM-1491578
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Tahir, Muhammad Abd al-Rahman& Salih, Kawthar Abd al-Jalil Muhammad& Muhammad, al-Hajj Nur al-Din& Babakir, Faysal Makki& Ismail, Ammar Muhammad. Association between inflammatory cytokines and liver functions in rheumatoid arthritis patients. Sudan Journal of Medical Sciences. 2021. Vol. 16, no. 2, pp.276-284.
https://search.emarefa.net/detail/BIM-1491578
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 282-284
رقم السجل
BIM-1491578
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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